MiR-218 regulates epithelial–mesenchymal transition and angiogenesis in colorectal cancer via targeting CTGF

MiR-218 regulates epithelial–mesenchymal transition and angiogenesis in colorectal cancer via targeting CTGF

Abstract Background Endothelial-to-mesenchymal transition (EMT) and angiogenesis play important roles in colorectal cancer (CRC) development. Connective tissue growth factor (CTGF) has been reported to promote several kinds of cancer progression and miR-218 has been identified as a tumor suppressor...

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Bibliographic Details
Main Authors: Weijian Lun, Xiongjian Wu, Qiliang Deng, Fachao Zhi
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Cancer Cell International
Subjects:
Colorectal cancer
miR-218
CTGF
EMT
Angiogenesis
Online Access:http://link.springer.com/article/10.1186/s12935-018-0575-2

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