A Case Report of Misdiagnosed Breast Implant-associated Anaplastic Large Cell Lymphoma with Lymphatic Extension
Summary:. Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare peripheral T-cell lymphoma associated with textured implants and usually presents as a late-onset periprosthetic seroma. We present a 70-year-old woman with a history of left breast invasive ductal carcinoma trea...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer
2021-11-01
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| Series: | Plastic and Reconstructive Surgery, Global Open |
| Online Access: | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000003916 |
| _version_ | 1818721416666677248 |
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| author | Dino Maglic, MD Whitney Moss, MD Giovanna Pires, BA Archana Agarwal, MD Cindy Matsen, MD Alvin Kwok, MD, MPH |
| author_facet | Dino Maglic, MD Whitney Moss, MD Giovanna Pires, BA Archana Agarwal, MD Cindy Matsen, MD Alvin Kwok, MD, MPH |
| author_sort | Dino Maglic, MD |
| collection | DOAJ |
| description | Summary:. Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare peripheral T-cell lymphoma associated with textured implants and usually presents as a late-onset periprosthetic seroma. We present a 70-year-old woman with a history of left breast invasive ductal carcinoma treated with mastectomy and textured implant-based reconstruction, and subsequent adjuvant chemotherapy due to lymphovascular extension. Eleven years following her reconstruction, the patient developed a periprosthetic seroma. Fine needle aspiration and partial capsulectomy were performed, but appropriate pathologic evaluation was not initially submitted. She then presented with lymphadenopathy, which was biopsied and revealed BIA-ALCL within an axillary lymph node. Despite implant explantation, complete capsulectomy, axillary lymph node dissection, and excision of groin lymphadenopathy, no evidence of primary ALCL was appreciated. This initially misdiagnosed case demonstrates the importance of following the National Comprehensive Cancer Network guidelines when a patient presents with late onset breast periprosthetic effusions. |
| first_indexed | 2024-12-17T20:38:23Z |
| format | Article |
| id | doaj.art-ab6e7aa467844ba39f4135b8c5308a95 |
| institution | Directory Open Access Journal |
| issn | 2169-7574 |
| language | English |
| last_indexed | 2024-12-17T20:38:23Z |
| publishDate | 2021-11-01 |
| publisher | Wolters Kluwer |
| record_format | Article |
| series | Plastic and Reconstructive Surgery, Global Open |
| spelling | doaj.art-ab6e7aa467844ba39f4135b8c5308a952022-12-21T21:33:23ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742021-11-01911e391610.1097/GOX.0000000000003916202111000-00017A Case Report of Misdiagnosed Breast Implant-associated Anaplastic Large Cell Lymphoma with Lymphatic ExtensionDino Maglic, MD0Whitney Moss, MD1Giovanna Pires, BA2Archana Agarwal, MD3Cindy Matsen, MD4Alvin Kwok, MD, MPH5From the * Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Utah School of Medicine, Salt Lake City, UtahFrom the * Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Utah School of Medicine, Salt Lake City, UtahFrom the * Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah† Division of Pathology University of Utah School of Medicine, Salt Lake City, Utah‡ Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah.From the * Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Utah School of Medicine, Salt Lake City, UtahSummary:. Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare peripheral T-cell lymphoma associated with textured implants and usually presents as a late-onset periprosthetic seroma. We present a 70-year-old woman with a history of left breast invasive ductal carcinoma treated with mastectomy and textured implant-based reconstruction, and subsequent adjuvant chemotherapy due to lymphovascular extension. Eleven years following her reconstruction, the patient developed a periprosthetic seroma. Fine needle aspiration and partial capsulectomy were performed, but appropriate pathologic evaluation was not initially submitted. She then presented with lymphadenopathy, which was biopsied and revealed BIA-ALCL within an axillary lymph node. Despite implant explantation, complete capsulectomy, axillary lymph node dissection, and excision of groin lymphadenopathy, no evidence of primary ALCL was appreciated. This initially misdiagnosed case demonstrates the importance of following the National Comprehensive Cancer Network guidelines when a patient presents with late onset breast periprosthetic effusions.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000003916 |
| spellingShingle | Dino Maglic, MD Whitney Moss, MD Giovanna Pires, BA Archana Agarwal, MD Cindy Matsen, MD Alvin Kwok, MD, MPH A Case Report of Misdiagnosed Breast Implant-associated Anaplastic Large Cell Lymphoma with Lymphatic Extension Plastic and Reconstructive Surgery, Global Open |
| title | A Case Report of Misdiagnosed Breast Implant-associated Anaplastic Large Cell Lymphoma with Lymphatic Extension |
| title_full | A Case Report of Misdiagnosed Breast Implant-associated Anaplastic Large Cell Lymphoma with Lymphatic Extension |
| title_fullStr | A Case Report of Misdiagnosed Breast Implant-associated Anaplastic Large Cell Lymphoma with Lymphatic Extension |
| title_full_unstemmed | A Case Report of Misdiagnosed Breast Implant-associated Anaplastic Large Cell Lymphoma with Lymphatic Extension |
| title_short | A Case Report of Misdiagnosed Breast Implant-associated Anaplastic Large Cell Lymphoma with Lymphatic Extension |
| title_sort | case report of misdiagnosed breast implant associated anaplastic large cell lymphoma with lymphatic extension |
| url | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000003916 |
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