STAU2 protein level is controlled by caspases and the CHK1 pathway and regulates cell cycle progression in the non-transformed hTERT-RPE1 cells

STAU2 protein level is controlled by caspases and the CHK1 pathway and regulates cell cycle progression in the non-transformed hTERT-RPE1 cells

Abstract Background Staufen2 (STAU2) is an RNA binding protein involved in the posttranscriptional regulation of gene expression. In neurons, STAU2 is required to maintain the balance between differentiation and proliferation of neural stem cells through asymmetric cell division. However, the import...

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Bibliographic Details
Main Authors: Lionel Condé, Yulemi Gonzalez Quesada, Florence Bonnet-Magnaval, Rémy Beaujois, Luc DesGroseillers
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Molecular and Cell Biology
Subjects:
Staufen2
CHK1
Caspase
Cell proliferation
Online Access:https://doi.org/10.1186/s12860-021-00352-y

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