Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines

Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines

Abstract Background Clonal VDJ rearrangement of B/T cell receptors (B/TCRs) occurring during B/T lymphocyte development has been used as a marker to track the clonality of B/T cell populations. Methods We systematically profiled the B/T cell receptor repertoire of 936 cancer cell lines across a vari...

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Main Authors: Kar-Tong Tan, Ling-Wen Ding, Qiao-Yang Sun, Zhen-Tang Lao, Wenwen Chien, Xi Ren, Jin-Fen Xiao, Xin Yi Loh, Liang Xu, Michael Lill, Anand Mayakonda, De-Chen Lin, Henry Yang, H. Phillip Koeffler
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Cancer
Subjects:
BCR/TCR receptor repertoire
EBV lymphocytes
Cancer cell lines
Online Access:http://link.springer.com/article/10.1186/s12885-018-4840-5

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