Porous Polymers from High Internal Phase Emulsions as Scaffolds for Biological Applications

High internal phase emulsions (HIPEs), with densely packed droplets of internal phase and monomers dispersed in the continuous phase, are now an established medium for porous polymer preparation (polyHIPEs). The ability to influence the pore size and interconnectivity, together with the process scal...

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Main Authors: Stanko Kramer, Neil R. Cameron, Peter Krajnc
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/13/11/1786
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author Stanko Kramer
Neil R. Cameron
Peter Krajnc
author_facet Stanko Kramer
Neil R. Cameron
Peter Krajnc
author_sort Stanko Kramer
collection DOAJ
description High internal phase emulsions (HIPEs), with densely packed droplets of internal phase and monomers dispersed in the continuous phase, are now an established medium for porous polymer preparation (polyHIPEs). The ability to influence the pore size and interconnectivity, together with the process scalability and a wide spectrum of possible chemistries are important advantages of polyHIPEs. In this review, the focus on the biomedical applications of polyHIPEs is emphasised, in particular the applications of polyHIPEs as scaffolds/supports for biological cell growth, proliferation and tissue (re)generation. An overview of the polyHIPE preparation methodology is given and possibilities of morphology tuning are outlined. In the continuation, polyHIPEs with different chemistries and their interaction with biological systems are described. A further focus is given to combined techniques and advanced applications.
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spelling doaj.art-ab7ac076217a4d96b6946208be7b670c2023-11-21T21:55:39ZengMDPI AGPolymers2073-43602021-05-011311178610.3390/polym13111786Porous Polymers from High Internal Phase Emulsions as Scaffolds for Biological ApplicationsStanko Kramer0Neil R. Cameron1Peter Krajnc2PolyOrgLab, Faculty of Chemistry and Chemical Engineering, University of Maribor, Smetanova ulica 17, 2000 Maribor, SloveniaDepartment of Materials Science and Engineering, Monash University, 22 Alliance Lane, Clayton, VIC 3800, AustraliaPolyOrgLab, Faculty of Chemistry and Chemical Engineering, University of Maribor, Smetanova ulica 17, 2000 Maribor, SloveniaHigh internal phase emulsions (HIPEs), with densely packed droplets of internal phase and monomers dispersed in the continuous phase, are now an established medium for porous polymer preparation (polyHIPEs). The ability to influence the pore size and interconnectivity, together with the process scalability and a wide spectrum of possible chemistries are important advantages of polyHIPEs. In this review, the focus on the biomedical applications of polyHIPEs is emphasised, in particular the applications of polyHIPEs as scaffolds/supports for biological cell growth, proliferation and tissue (re)generation. An overview of the polyHIPE preparation methodology is given and possibilities of morphology tuning are outlined. In the continuation, polyHIPEs with different chemistries and their interaction with biological systems are described. A further focus is given to combined techniques and advanced applications.https://www.mdpi.com/2073-4360/13/11/1786polyHIPEtissue engineeringcell culturingemulsion templatingporous polymersbiodegradable polymers
spellingShingle Stanko Kramer
Neil R. Cameron
Peter Krajnc
Porous Polymers from High Internal Phase Emulsions as Scaffolds for Biological Applications
Polymers
polyHIPE
tissue engineering
cell culturing
emulsion templating
porous polymers
biodegradable polymers
title Porous Polymers from High Internal Phase Emulsions as Scaffolds for Biological Applications
title_full Porous Polymers from High Internal Phase Emulsions as Scaffolds for Biological Applications
title_fullStr Porous Polymers from High Internal Phase Emulsions as Scaffolds for Biological Applications
title_full_unstemmed Porous Polymers from High Internal Phase Emulsions as Scaffolds for Biological Applications
title_short Porous Polymers from High Internal Phase Emulsions as Scaffolds for Biological Applications
title_sort porous polymers from high internal phase emulsions as scaffolds for biological applications
topic polyHIPE
tissue engineering
cell culturing
emulsion templating
porous polymers
biodegradable polymers
url https://www.mdpi.com/2073-4360/13/11/1786
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