The Diverse Roles of Heme Oxygenase-1 in Tumor Progression
Heme oxygenase-1 (HO-1) is an inducible intracellular enzyme that is expressed in response to a variety of stimuli to degrade heme, which generates the biologically active catabolites carbon monoxide (CO), biliverdin and ferrous iron (Fe2+). HO-1 is expressed across a range of cancers and has been d...
Main Authors: | Kim Ngan Luu Hoang, Joanne E. Anstee, James N. Arnold |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-03-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2021.658315/full |
Similar Items
-
Cytoprotective Role of Heme Oxygenase-1 in Cancer Chemoresistance: Focus on Antioxidant, Antiapoptotic, and Pro-Autophagy Properties
by: Huan Wang, et al.
Published: (2023-06-01) -
Regulation of Complement Activation by Heme Oxygenase-1 (HO-1) in Kidney Injury
by: Maria G. Detsika, et al.
Published: (2021-01-01) -
Effect of Heme Oxygenase-1 Depletion on Complement Regulatory Proteins Expression in the Rat
by: Maria G. Detsika, et al.
Published: (2022-12-01) -
Reprograming of Tumor-Associated Macrophages in Breast Tumor-Bearing Mice under Chemotherapy by Targeting Heme Oxygenase-1
by: Seung Hyeon Kim, et al.
Published: (2021-03-01) -
Absence of Heme Oxygenase-1 Affects Trophoblastic Spheroid Implantation and Provokes Dysregulation of Stress and Angiogenesis Gene Expression in the Uterus
by: Maria Laura Zenclussen, et al.
Published: (2024-02-01)