Manufacture of a Stable Lyophilized Formulation of the Live Attenuated Pertussis Vaccine BPZE1

Manufacture of a Stable Lyophilized Formulation of the Live Attenuated Pertussis Vaccine BPZE1

Current pertussis vaccines protect against disease, but not against colonization by and transmission of <i>Bordetella pertussis</i>, whereas natural infection protects against both. The live attenuated vaccine BPZE1 was developed to mimic immunogenicity of natural infection without causi...

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Bibliographic Details
Main Authors: Marcel Thalen, Anne-Sophie Debrie, Loic Coutte, Dominique Raze, Ken Solovay, Keith Rubin, Nathalie Mielcarek, Camille Locht
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Vaccines
Subjects:
pertussis
live attenuated vaccine
lyophilization
vaccine stability
Online Access:https://www.mdpi.com/2076-393X/8/3/523

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