Printability–A key issue in extrusion-based bioprinting
Three-dimensional (3D) extrusion-based bioprinting is widely used in tissue engineering and regenerative medicine to create cell-incorporated constructs or scaffolds based on the extrusion technique. One critical issue in 3D extrusion-based bioprinting is printability or the capability to form and m...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-10-01
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| Series: | Journal of Pharmaceutical Analysis |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2095177921000162 |
| _version_ | 1818933955637805056 |
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| author | Saman Naghieh Xiongbiao Chen |
| author_facet | Saman Naghieh Xiongbiao Chen |
| author_sort | Saman Naghieh |
| collection | DOAJ |
| description | Three-dimensional (3D) extrusion-based bioprinting is widely used in tissue engineering and regenerative medicine to create cell-incorporated constructs or scaffolds based on the extrusion technique. One critical issue in 3D extrusion-based bioprinting is printability or the capability to form and maintain reproducible 3D scaffolds from bioink (a mixture of biomaterials and cells). Research shows that printability can be affected by many factors or parameters, including those associated with the bioink, printing process, and scaffold design, but these are far from certain. This review highlights recent developments in the printability assessment of extrusion-based bioprinting with a focus on the definition of printability, printability measurements and characterization, and printability-affecting factors. Key issues and challenges related to printability are also identified and discussed, along with approaches or strategies for improving printability in extrusion-based bioprinting. |
| first_indexed | 2024-12-20T04:56:36Z |
| format | Article |
| id | doaj.art-ab80975dfb8e45909ae84a1fff0f16e8 |
| institution | Directory Open Access Journal |
| issn | 2095-1779 |
| language | English |
| last_indexed | 2024-12-20T04:56:36Z |
| publishDate | 2021-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Pharmaceutical Analysis |
| spelling | doaj.art-ab80975dfb8e45909ae84a1fff0f16e82022-12-21T19:52:42ZengElsevierJournal of Pharmaceutical Analysis2095-17792021-10-01115564579Printability–A key issue in extrusion-based bioprintingSaman Naghieh0Xiongbiao Chen1Division of Biomedical Engineering, College of Engineering, University of Saskatchewan, Saskatoon, SK, S7N 5A9, Canada; Corresponding author.Division of Biomedical Engineering, College of Engineering, University of Saskatchewan, Saskatoon, SK, S7N 5A9, Canada; Department of Mechanical Engineering, College of Engineering, University of Saskatchewan, Saskatoon, SK, S7N 5A9, Canada; Corresponding author. Division of Biomedical Engineering, College of Engineering, University of Saskatchewan, Saskatoon, SK, S7N 5A9, Canada.Three-dimensional (3D) extrusion-based bioprinting is widely used in tissue engineering and regenerative medicine to create cell-incorporated constructs or scaffolds based on the extrusion technique. One critical issue in 3D extrusion-based bioprinting is printability or the capability to form and maintain reproducible 3D scaffolds from bioink (a mixture of biomaterials and cells). Research shows that printability can be affected by many factors or parameters, including those associated with the bioink, printing process, and scaffold design, but these are far from certain. This review highlights recent developments in the printability assessment of extrusion-based bioprinting with a focus on the definition of printability, printability measurements and characterization, and printability-affecting factors. Key issues and challenges related to printability are also identified and discussed, along with approaches or strategies for improving printability in extrusion-based bioprinting.http://www.sciencedirect.com/science/article/pii/S2095177921000162Extrusion3D bioprintingBioinkPrintabilityTissue engineering |
| spellingShingle | Saman Naghieh Xiongbiao Chen Printability–A key issue in extrusion-based bioprinting Journal of Pharmaceutical Analysis Extrusion 3D bioprinting Bioink Printability Tissue engineering |
| title | Printability–A key issue in extrusion-based bioprinting |
| title_full | Printability–A key issue in extrusion-based bioprinting |
| title_fullStr | Printability–A key issue in extrusion-based bioprinting |
| title_full_unstemmed | Printability–A key issue in extrusion-based bioprinting |
| title_short | Printability–A key issue in extrusion-based bioprinting |
| title_sort | printability a key issue in extrusion based bioprinting |
| topic | Extrusion 3D bioprinting Bioink Printability Tissue engineering |
| url | http://www.sciencedirect.com/science/article/pii/S2095177921000162 |
| work_keys_str_mv | AT samannaghieh printabilityakeyissueinextrusionbasedbioprinting AT xiongbiaochen printabilityakeyissueinextrusionbasedbioprinting |