miRNA nanoencapsulation to regulate the programming of the blood-brain barrier permeability by hypoxia

miRNA nanoencapsulation to regulate the programming of the blood-brain barrier permeability by hypoxia

Central nervous system (CNS)-related diseases are difficult to treat as most therapeutic agents they cannot reach the brain tissue, mainly due to the blood-brain barrier (BBB), arguably the tightest barrier between the human body and cerebral parenchyma, which routinely excludes most xenobiotic ther...

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Bibliographic Details
Main Authors: Esteban G. Figueroa, Aitor Caballero-Román, Josep R. Ticó, Montserrat Miñarro, Anna Nardi-Ricart, Alejandro González-Candia
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Current Research in Pharmacology and Drug Discovery
Subjects:
miRNA
Epigenetic
Hypoxia
Nanoparticle
Nose-to-brain
Online Access:http://www.sciencedirect.com/science/article/pii/S2590257122000499

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