Novel non-pharmacological insomnia treatment – a pilot study
Milena K Pavlova,1 Véronique Latreille,1 Nirajan Puri,1 Jami Johnsen,1 Salma Batool-Anwar,2 Sogol Javaheri,2 Paul G Mathew1 1Department of Neurology, Harvard Medical School, Brigham and Women’s Hospital, Boston, MA, USA; 2Department of Medicine, Harvard Medical School, Brigham a...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2019-09-01
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| Series: | Nature and Science of Sleep |
| Subjects: | |
| Online Access: | https://www.dovepress.com/novel-non-pharmacological-insomnia-treatment-a-pilot-study-peer-reviewed-article-NSS |
| _version_ | 1818893494876372992 |
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| author | Pavlova MK Latreille V Puri N Johnsen J Batool-Anwar S Javaheri S Mathew PG |
| author_facet | Pavlova MK Latreille V Puri N Johnsen J Batool-Anwar S Javaheri S Mathew PG |
| author_sort | Pavlova MK |
| collection | DOAJ |
| description | Milena K Pavlova,1 Véronique Latreille,1 Nirajan Puri,1 Jami Johnsen,1 Salma Batool-Anwar,2 Sogol Javaheri,2 Paul G Mathew1 1Department of Neurology, Harvard Medical School, Brigham and Women’s Hospital, Boston, MA, USA; 2Department of Medicine, Harvard Medical School, Brigham and Women’s Hospital, Boston, MA, USACorrespondence: Milena K PavlovaDepartment of Neurology, Brigham and Women’s Hospital, 75 Francis Street, Boston, MA 02115, USATel +1 617 983 7580Fax +1 617 983 7582Email mpavlova@bwh.harvard.eduObjective: The objective of this prospective pilot study was to examine the effects of a novel non-pharmacological device (BioBoosti) on insomnia symptoms in adults.Methods: Subjects with chronic insomnia were instructed to hold the device in each hand for 8 mins for 6 cycles on a nightly basis for 2 weeks. Outcomes tested included standardized subjective sleep measures assessing sleep quality, insomnia symptoms, and daytime sleepiness. Sleep was objectively quantified using electroencephalogram (EEG) before and after 2 weeks of treatment with BioBoosti, and wrist actigraphy throughout the study.Results: Twenty adults (mean age: 45.6±17.1 y/o; range 18–74 y/o) were enrolled in the study. No significant side effects were noted by any of the subjects. After 2 weeks of BioBoosti use, subjects reported improved sleep quality (Pittsburgh Sleep Quality Index: 12.6±3.3 versus 8.5±3.7, p=0.001) and reduced insomnia symptoms (Insomnia Severity Index: 18.2±5.2 versus 12.8±7.0, p<0.001). Sleepiness, as assessed by a visual analog scale, was significantly reduced after treatment (5.7±2.8 versus 4.0±3.3, p=0.03).Conclusion: BioBoosti use yielded an improvement in insomnia symptoms. Larger placebo-controlled studies are needed to fully assess efficacy.Keywords: insomnia, non-pharmacological treatment, sleep quality, actigraphy, electroencephalography |
| first_indexed | 2024-12-19T18:13:30Z |
| format | Article |
| id | doaj.art-ab84b2c4d86a45089973c95743e383e2 |
| institution | Directory Open Access Journal |
| issn | 1179-1608 |
| language | English |
| last_indexed | 2024-12-19T18:13:30Z |
| publishDate | 2019-09-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Nature and Science of Sleep |
| spelling | doaj.art-ab84b2c4d86a45089973c95743e383e22022-12-21T20:11:13ZengDove Medical PressNature and Science of Sleep1179-16082019-09-01Volume 1118919548515Novel non-pharmacological insomnia treatment – a pilot studyPavlova MKLatreille VPuri NJohnsen JBatool-Anwar SJavaheri SMathew PGMilena K Pavlova,1 Véronique Latreille,1 Nirajan Puri,1 Jami Johnsen,1 Salma Batool-Anwar,2 Sogol Javaheri,2 Paul G Mathew1 1Department of Neurology, Harvard Medical School, Brigham and Women’s Hospital, Boston, MA, USA; 2Department of Medicine, Harvard Medical School, Brigham and Women’s Hospital, Boston, MA, USACorrespondence: Milena K PavlovaDepartment of Neurology, Brigham and Women’s Hospital, 75 Francis Street, Boston, MA 02115, USATel +1 617 983 7580Fax +1 617 983 7582Email mpavlova@bwh.harvard.eduObjective: The objective of this prospective pilot study was to examine the effects of a novel non-pharmacological device (BioBoosti) on insomnia symptoms in adults.Methods: Subjects with chronic insomnia were instructed to hold the device in each hand for 8 mins for 6 cycles on a nightly basis for 2 weeks. Outcomes tested included standardized subjective sleep measures assessing sleep quality, insomnia symptoms, and daytime sleepiness. Sleep was objectively quantified using electroencephalogram (EEG) before and after 2 weeks of treatment with BioBoosti, and wrist actigraphy throughout the study.Results: Twenty adults (mean age: 45.6±17.1 y/o; range 18–74 y/o) were enrolled in the study. No significant side effects were noted by any of the subjects. After 2 weeks of BioBoosti use, subjects reported improved sleep quality (Pittsburgh Sleep Quality Index: 12.6±3.3 versus 8.5±3.7, p=0.001) and reduced insomnia symptoms (Insomnia Severity Index: 18.2±5.2 versus 12.8±7.0, p<0.001). Sleepiness, as assessed by a visual analog scale, was significantly reduced after treatment (5.7±2.8 versus 4.0±3.3, p=0.03).Conclusion: BioBoosti use yielded an improvement in insomnia symptoms. Larger placebo-controlled studies are needed to fully assess efficacy.Keywords: insomnia, non-pharmacological treatment, sleep quality, actigraphy, electroencephalographyhttps://www.dovepress.com/novel-non-pharmacological-insomnia-treatment-a-pilot-study-peer-reviewed-article-NSSInsomnianon-pharmacological treatmentsleep qualityactigraphyelectroencephalography |
| spellingShingle | Pavlova MK Latreille V Puri N Johnsen J Batool-Anwar S Javaheri S Mathew PG Novel non-pharmacological insomnia treatment – a pilot study Nature and Science of Sleep Insomnia non-pharmacological treatment sleep quality actigraphy electroencephalography |
| title | Novel non-pharmacological insomnia treatment – a pilot study |
| title_full | Novel non-pharmacological insomnia treatment – a pilot study |
| title_fullStr | Novel non-pharmacological insomnia treatment – a pilot study |
| title_full_unstemmed | Novel non-pharmacological insomnia treatment – a pilot study |
| title_short | Novel non-pharmacological insomnia treatment – a pilot study |
| title_sort | novel non pharmacological insomnia treatment ndash a pilot study |
| topic | Insomnia non-pharmacological treatment sleep quality actigraphy electroencephalography |
| url | https://www.dovepress.com/novel-non-pharmacological-insomnia-treatment-a-pilot-study-peer-reviewed-article-NSS |
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