Dextromethorphan Reduces Postoperative Pain of Post Partum Tubal Ligation under General Anesthesia

Introduction & Objective: Postoperative pain has harmful effects in many systems. Dextromethorphan reduces postoperative pain in post partum tubal ligation under general anesthesia. Materials & Methods: In this research 40 patients with ASA class I and II in double blind randomized clinical...

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Main Authors: Nahid Manochehrian, Seyyed Majid Hashemi Fesharaki, Pooran Hajian, Ebrahim Khoshraftar
Format: Article
Language:fas
Published: Hamadan University of Medical Sciences 2009-06-01
Series:پزشکی بالینی ابن سینا
Subjects:
Online Access:http://sjh.umsha.ac.ir/article-1-329-en.html
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author Nahid Manochehrian
Seyyed Majid Hashemi Fesharaki
Pooran Hajian
Ebrahim Khoshraftar
author_facet Nahid Manochehrian
Seyyed Majid Hashemi Fesharaki
Pooran Hajian
Ebrahim Khoshraftar
author_sort Nahid Manochehrian
collection DOAJ
description Introduction & Objective: Postoperative pain has harmful effects in many systems. Dextromethorphan reduces postoperative pain in post partum tubal ligation under general anesthesia. Materials & Methods: In this research 40 patients with ASA class I and II in double blind randomized clinical trial were studied in two groups. 90 minutes before surgery the patients received 90 mg dextromethorphan or placebo (oral). The patients induced general anesthesia with thiopental (5mg/kg), fentanyl 1.5 mg/kg and succinylcholine (1-1.5 mg/kg) and maintenance with halothane and N2O 50%. Patients were observed studied for analgesic requirement, nausea, vomiting, urinary retention and respiratory depression in recovery and 2,4,8 and 24 hours after surgery. Results: There was no significant difference in age, education, . . . Pain in recovery, 2 and 4 hours after surgery in dextromethorphan was less than placebo group. The analgesic requirement (pethidine) in dextromethophan was less than placebo group. Conclusion: Administration of 90 mg dextromethorphan 90 minutes before the surgery under GA reduces pain in recovery time , 2 and 4 hours after the surgery.
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spelling doaj.art-ab8846f5b15c4836bfc42c1665cb9ef72022-12-21T21:46:33ZfasHamadan University of Medical Sciencesپزشکی بالینی ابن سینا2588-722X2588-72382009-06-011612327Dextromethorphan Reduces Postoperative Pain of Post Partum Tubal Ligation under General AnesthesiaNahid Manochehrian0Seyyed Majid Hashemi Fesharaki1Pooran Hajian2Ebrahim Khoshraftar3 Introduction & Objective: Postoperative pain has harmful effects in many systems. Dextromethorphan reduces postoperative pain in post partum tubal ligation under general anesthesia. Materials & Methods: In this research 40 patients with ASA class I and II in double blind randomized clinical trial were studied in two groups. 90 minutes before surgery the patients received 90 mg dextromethorphan or placebo (oral). The patients induced general anesthesia with thiopental (5mg/kg), fentanyl 1.5 mg/kg and succinylcholine (1-1.5 mg/kg) and maintenance with halothane and N2O 50%. Patients were observed studied for analgesic requirement, nausea, vomiting, urinary retention and respiratory depression in recovery and 2,4,8 and 24 hours after surgery. Results: There was no significant difference in age, education, . . . Pain in recovery, 2 and 4 hours after surgery in dextromethorphan was less than placebo group. The analgesic requirement (pethidine) in dextromethophan was less than placebo group. Conclusion: Administration of 90 mg dextromethorphan 90 minutes before the surgery under GA reduces pain in recovery time , 2 and 4 hours after the surgery.http://sjh.umsha.ac.ir/article-1-329-en.htmlpaindextromethorphansterilizationtubal
spellingShingle Nahid Manochehrian
Seyyed Majid Hashemi Fesharaki
Pooran Hajian
Ebrahim Khoshraftar
Dextromethorphan Reduces Postoperative Pain of Post Partum Tubal Ligation under General Anesthesia
پزشکی بالینی ابن سینا
pain
dextromethorphan
sterilization
tubal
title Dextromethorphan Reduces Postoperative Pain of Post Partum Tubal Ligation under General Anesthesia
title_full Dextromethorphan Reduces Postoperative Pain of Post Partum Tubal Ligation under General Anesthesia
title_fullStr Dextromethorphan Reduces Postoperative Pain of Post Partum Tubal Ligation under General Anesthesia
title_full_unstemmed Dextromethorphan Reduces Postoperative Pain of Post Partum Tubal Ligation under General Anesthesia
title_short Dextromethorphan Reduces Postoperative Pain of Post Partum Tubal Ligation under General Anesthesia
title_sort dextromethorphan reduces postoperative pain of post partum tubal ligation under general anesthesia
topic pain
dextromethorphan
sterilization
tubal
url http://sjh.umsha.ac.ir/article-1-329-en.html
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AT pooranhajian dextromethorphanreducespostoperativepainofpostpartumtuballigationundergeneralanesthesia
AT ebrahimkhoshraftar dextromethorphanreducespostoperativepainofpostpartumtuballigationundergeneralanesthesia