Comparison of human papillomavirus (HPV) detection in urine and cervical swab samples using the HPV GenoArray Diagnostic assay
Human papillomavirus (HPV) is the leading cause of cervical cancer. Urine-based HPV testing offers a simple and non-invasive method because of its increasing acceptance. A total of 164 pairs of cervical swab and urine samples from Thai women who underwent cervical cancer screening were used for HPV...
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| Format: | Article |
| Language: | English |
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PeerJ Inc.
2017-10-01
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| Series: | PeerJ |
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| Online Access: | https://peerj.com/articles/3910.pdf |
| _version_ | 1797424410752188416 |
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| author | Pornjarim Nilyanimit Jira Chansaenroj Anant Karalak Piyawat Laowahutanont Pairoj Junyangdikul Yong Poovorawan |
| author_facet | Pornjarim Nilyanimit Jira Chansaenroj Anant Karalak Piyawat Laowahutanont Pairoj Junyangdikul Yong Poovorawan |
| author_sort | Pornjarim Nilyanimit |
| collection | DOAJ |
| description | Human papillomavirus (HPV) is the leading cause of cervical cancer. Urine-based HPV testing offers a simple and non-invasive method because of its increasing acceptance. A total of 164 pairs of cervical swab and urine samples from Thai women who underwent cervical cancer screening were used for HPV testing with HPV GenoArray Diagnostic Kits. The overall concordance percentage for HPV detection in the cervical swab and urine samples was 65.2%. The HPV genotypes most commonly detected were HPV16 and HPV18. An analysis of the urine samples and a second analysis of the cervical swab samples showed that the differences in the overall HPV detection rate between women with normal and abnormal cytology were not significant (p > 0.05). Urine samples processed with the GenoArray assay is an alternative for women who decline to undergo Pap smear even though it is not ideal as the first-line screening option. |
| first_indexed | 2024-03-09T08:01:51Z |
| format | Article |
| id | doaj.art-ab885b4dfaa340f49e0c2b9a87425e21 |
| institution | Directory Open Access Journal |
| issn | 2167-8359 |
| language | English |
| last_indexed | 2024-03-09T08:01:51Z |
| publishDate | 2017-10-01 |
| publisher | PeerJ Inc. |
| record_format | Article |
| series | PeerJ |
| spelling | doaj.art-ab885b4dfaa340f49e0c2b9a87425e212023-12-03T00:41:30ZengPeerJ Inc.PeerJ2167-83592017-10-015e391010.7717/peerj.3910Comparison of human papillomavirus (HPV) detection in urine and cervical swab samples using the HPV GenoArray Diagnostic assayPornjarim Nilyanimit0Jira Chansaenroj1Anant Karalak2Piyawat Laowahutanont3Pairoj Junyangdikul4Yong Poovorawan5Center of Excellence in Clinical Virology, Faculty of Medicine, Chulalongkorn University, Bangkok, ThailandCenter of Excellence in Clinical Virology, Faculty of Medicine, Chulalongkorn University, Bangkok, ThailandDepartment of Pathology, National Cancer Institute, Bangkok, ThailandDepartment of Gynecology, National Cancer Institute, Bangkok, ThailandDepartment of Pathology, Samitivej Srinakarin Hospital, Bangkok Hospital Group, Bangkok, ThailandCenter of Excellence in Clinical Virology, Faculty of Medicine, Chulalongkorn University, Bangkok, ThailandHuman papillomavirus (HPV) is the leading cause of cervical cancer. Urine-based HPV testing offers a simple and non-invasive method because of its increasing acceptance. A total of 164 pairs of cervical swab and urine samples from Thai women who underwent cervical cancer screening were used for HPV testing with HPV GenoArray Diagnostic Kits. The overall concordance percentage for HPV detection in the cervical swab and urine samples was 65.2%. The HPV genotypes most commonly detected were HPV16 and HPV18. An analysis of the urine samples and a second analysis of the cervical swab samples showed that the differences in the overall HPV detection rate between women with normal and abnormal cytology were not significant (p > 0.05). Urine samples processed with the GenoArray assay is an alternative for women who decline to undergo Pap smear even though it is not ideal as the first-line screening option.https://peerj.com/articles/3910.pdfHPVUrineGenotypingCervical cancer |
| spellingShingle | Pornjarim Nilyanimit Jira Chansaenroj Anant Karalak Piyawat Laowahutanont Pairoj Junyangdikul Yong Poovorawan Comparison of human papillomavirus (HPV) detection in urine and cervical swab samples using the HPV GenoArray Diagnostic assay PeerJ HPV Urine Genotyping Cervical cancer |
| title | Comparison of human papillomavirus (HPV) detection in urine and cervical swab samples using the HPV GenoArray Diagnostic assay |
| title_full | Comparison of human papillomavirus (HPV) detection in urine and cervical swab samples using the HPV GenoArray Diagnostic assay |
| title_fullStr | Comparison of human papillomavirus (HPV) detection in urine and cervical swab samples using the HPV GenoArray Diagnostic assay |
| title_full_unstemmed | Comparison of human papillomavirus (HPV) detection in urine and cervical swab samples using the HPV GenoArray Diagnostic assay |
| title_short | Comparison of human papillomavirus (HPV) detection in urine and cervical swab samples using the HPV GenoArray Diagnostic assay |
| title_sort | comparison of human papillomavirus hpv detection in urine and cervical swab samples using the hpv genoarray diagnostic assay |
| topic | HPV Urine Genotyping Cervical cancer |
| url | https://peerj.com/articles/3910.pdf |
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