A Marine Anthraquinone SZ-685C Overrides Adriamycin-Resistance in Breast Cancer Cells through Suppressing Akt Signaling

A Marine Anthraquinone SZ-685C Overrides Adriamycin-Resistance in Breast Cancer Cells through Suppressing Akt Signaling

Breast cancer remains a major health problem worldwide. While chemotherapy represents an important therapeutic modality against breast cancer, limitations in the clinical use of chemotherapy remain formidable because of chemoresistance. The HER2/PI-3K/Akt pathway has been demonstrated to play a caus...

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Bibliographic Details
Main Authors: Mengfeng Li, Yongcheng Lin, Zhigang She, Shengping Chen, Lili Zhong, Hong Chen, Henan Zhang, Wan Yang, Min Lin, Qianhui Zhang, Cuiji Lin, Yiwen Hu, Yi Jiang, Jie Yuan, Weitao Wen, Zhenjian He, Jueheng Wu, Xun Zhu
Format: Article
Language:English
Published: MDPI AG 2012-03-01
Series:Marine Drugs
Subjects:
SZ-685C
breast cancer
chemoresistance
Akt
Online Access:http://www.mdpi.com/1660-3397/10/4/694/

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