Adhesion to the Brain Endothelium Selects Breast Cancer Cells with Brain Metastasis Potential

Adhesion to the Brain Endothelium Selects Breast Cancer Cells with Brain Metastasis Potential

Tumor cells metastasize from a primary lesion to distant organs mainly through hematogenous dissemination, in which tumor cell re-adhesion to the endothelium is essential before extravasating into the target site. We thus hypothesize that tumor cells with the ability to adhere to the endothelium of...

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Bibliographic Details
Main Authors: Bai Zhang, Xueyi Li, Kai Tang, Ying Xin, Guanshuo Hu, Yufan Zheng, Keming Li, Cunyu Zhang, Youhua Tan
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
endothelial adhesion
biomechanics
mechanobiology
fluid shear stress
brain metastasis
Online Access:https://www.mdpi.com/1422-0067/24/8/7087

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