When a Goitre is a Thyroid Lymphoma

Primary thyroid lymphoma is a rare cause of both thyroid malignancy and extra-nodal lymphoma. It typically presents as a rapidly enlarging goitre with compressive symptoms. Histological analysis of a biopsy specimen is necessary to confirm the diagnosis. Awareness of this disease is important for ea...

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Main Authors: Mariana de Aguiar Gonçalves, Elsa Gaspar, Lèlita Santos, Armando Carvalho
Format: Article
Language:English
Published: SMC MEDIA SRL 2018-12-01
Series:European Journal of Case Reports in Internal Medicine
Subjects:
Online Access:https://www.ejcrim.com/index.php/EJCRIM/article/view/999
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author Mariana de Aguiar Gonçalves
Elsa Gaspar
Lèlita Santos
Armando Carvalho
author_facet Mariana de Aguiar Gonçalves
Elsa Gaspar
Lèlita Santos
Armando Carvalho
author_sort Mariana de Aguiar Gonçalves
collection DOAJ
description Primary thyroid lymphoma is a rare cause of both thyroid malignancy and extra-nodal lymphoma. It typically presents as a rapidly enlarging goitre with compressive symptoms. Histological analysis of a biopsy specimen is necessary to confirm the diagnosis. Awareness of this disease is important for early diagnosis and appropriate treatment. A 55-year-old man was admitted due to a 3-month history of cervical enlargement, facial and periorbital oedema and dyspnoea, apparently due to a superior vena cava syndrome. However, cervical ultrasound showed asymmetrical thyroid enlargement, lobulated contours and a hypoechogenic texture. A neck CT scan showed calibre reduction of the superior vena cava. The diagnosis of primary thyroid lymphoma was confirmed by open biopsy of the thyroid gland. The patient started treatment with rituximab with clinical improvement.
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spelling doaj.art-ab8df111212b442cafcda56df8d194c82022-12-22T01:13:31ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942018-12-0110.12890/2018_000999999When a Goitre is a Thyroid LymphomaMariana de Aguiar Gonçalves0Elsa Gaspar1Lèlita Santos2Armando Carvalho3Internal Medicine Department, Centro Hospitalar e Universitário de Coimbra, PortugalInternal Medicine Department, Centro Hospitalar e Universitário de Coimbra, PortugalInternal Medicine Department, Centro Hospitalar e Universitário de Coimbra, PortugalInternal Medicine Department, Centro Hospitalar e Universitário de Coimbra, PortugalPrimary thyroid lymphoma is a rare cause of both thyroid malignancy and extra-nodal lymphoma. It typically presents as a rapidly enlarging goitre with compressive symptoms. Histological analysis of a biopsy specimen is necessary to confirm the diagnosis. Awareness of this disease is important for early diagnosis and appropriate treatment. A 55-year-old man was admitted due to a 3-month history of cervical enlargement, facial and periorbital oedema and dyspnoea, apparently due to a superior vena cava syndrome. However, cervical ultrasound showed asymmetrical thyroid enlargement, lobulated contours and a hypoechogenic texture. A neck CT scan showed calibre reduction of the superior vena cava. The diagnosis of primary thyroid lymphoma was confirmed by open biopsy of the thyroid gland. The patient started treatment with rituximab with clinical improvement.https://www.ejcrim.com/index.php/EJCRIM/article/view/999Cervical enlargementprimary thyroid lymphomaextra-nodal lymphoma
spellingShingle Mariana de Aguiar Gonçalves
Elsa Gaspar
Lèlita Santos
Armando Carvalho
When a Goitre is a Thyroid Lymphoma
European Journal of Case Reports in Internal Medicine
Cervical enlargement
primary thyroid lymphoma
extra-nodal lymphoma
title When a Goitre is a Thyroid Lymphoma
title_full When a Goitre is a Thyroid Lymphoma
title_fullStr When a Goitre is a Thyroid Lymphoma
title_full_unstemmed When a Goitre is a Thyroid Lymphoma
title_short When a Goitre is a Thyroid Lymphoma
title_sort when a goitre is a thyroid lymphoma
topic Cervical enlargement
primary thyroid lymphoma
extra-nodal lymphoma
url https://www.ejcrim.com/index.php/EJCRIM/article/view/999
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