Anti-adhesive Strategy in Development of Combined Antidiphtheritic Vaccine as a Perspective Preventive Measure of Corynebacteria diphtheriae Circulation Among the Population

A study is devoted to the development of new bacterial diphtheria vaccines aimed at prevention adhesion of microbial cells to host’s pharyngeal epithelial cells and thus limit colonization of mucous membranes, bacteria carrier state formation and promoted to C. diphtheriaе circulation decrease among...

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Main Authors: I. V. Yelyseyeva, Ye. M. Babich, L. A. Zhdamarova, V. I. Belozersky, Ye. Yu. Isayenko, S. A. Kolpak
Format: Article
Language:Russian
Published: LLC "Diagnostics and Vaccines" 2015-10-01
Series:Детские инфекции (Москва)
Subjects:
Online Access:https://detinf.elpub.ru/jour/article/view/167
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author I. V. Yelyseyeva
Ye. M. Babich
L. A. Zhdamarova
V. I. Belozersky
Ye. Yu. Isayenko
S. A. Kolpak
author_facet I. V. Yelyseyeva
Ye. M. Babich
L. A. Zhdamarova
V. I. Belozersky
Ye. Yu. Isayenko
S. A. Kolpak
author_sort I. V. Yelyseyeva
collection DOAJ
description A study is devoted to the development of new bacterial diphtheria vaccines aimed at prevention adhesion of microbial cells to host’s pharyngeal epithelial cells and thus limit colonization of mucous membranes, bacteria carrier state formation and promoted to C. diphtheriaе circulation decrease among the population. As a base of the candidate-vaccine we suggest the diphtheria bacterial antigenic preparation obtained by use of electro-magnetic radiation of ultrahigh frequency from a culture of C. diphtheriaе, var. gravis, tox +.
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language Russian
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publisher LLC "Diagnostics and Vaccines"
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spelling doaj.art-ab94fce0ea104ed08c9375f0a967b2092025-03-05T13:50:42ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072015-10-01143303310.22627/2072-8107-2015-14-3-30-33167Anti-adhesive Strategy in Development of Combined Antidiphtheritic Vaccine as a Perspective Preventive Measure of Corynebacteria diphtheriae Circulation Among the PopulationI. V. Yelyseyeva0Ye. M. Babich1L. A. Zhdamarova2V. I. Belozersky3Ye. Yu. Isayenko4S. A. Kolpak5State Institution «Mechnikov Institute of Microbiology and Immunology of National Academy of Medical Science of Ukraine», Kharkov, UkraineState Institution «Mechnikov Institute of Microbiology and Immunology of National Academy of Medical Science of Ukraine», Kharkov, UkraineState Institution «Mechnikov Institute of Microbiology and Immunology of National Academy of Medical Science of Ukraine», Kharkov, UkraineState Institution «Mechnikov Institute of Microbiology and Immunology of National Academy of Medical Science of Ukraine», Kharkov, UkraineState Institution «Mechnikov Institute of Microbiology and Immunology of National Academy of Medical Science of Ukraine», Kharkov, UkraineState Institution «Mechnikov Institute of Microbiology and Immunology of National Academy of Medical Science of Ukraine», Kharkov, UkraineA study is devoted to the development of new bacterial diphtheria vaccines aimed at prevention adhesion of microbial cells to host’s pharyngeal epithelial cells and thus limit colonization of mucous membranes, bacteria carrier state formation and promoted to C. diphtheriaе circulation decrease among the population. As a base of the candidate-vaccine we suggest the diphtheria bacterial antigenic preparation obtained by use of electro-magnetic radiation of ultrahigh frequency from a culture of C. diphtheriaе, var. gravis, tox +.https://detinf.elpub.ru/jour/article/view/167diphtheria vaccinesc. diphtheriaеdiphtheria bacterial antigensadhesionelectromagnetic radiation of microwave frequency
spellingShingle I. V. Yelyseyeva
Ye. M. Babich
L. A. Zhdamarova
V. I. Belozersky
Ye. Yu. Isayenko
S. A. Kolpak
Anti-adhesive Strategy in Development of Combined Antidiphtheritic Vaccine as a Perspective Preventive Measure of Corynebacteria diphtheriae Circulation Among the Population
Детские инфекции (Москва)
diphtheria vaccines
c. diphtheriaе
diphtheria bacterial antigens
adhesion
electromagnetic radiation of microwave frequency
title Anti-adhesive Strategy in Development of Combined Antidiphtheritic Vaccine as a Perspective Preventive Measure of Corynebacteria diphtheriae Circulation Among the Population
title_full Anti-adhesive Strategy in Development of Combined Antidiphtheritic Vaccine as a Perspective Preventive Measure of Corynebacteria diphtheriae Circulation Among the Population
title_fullStr Anti-adhesive Strategy in Development of Combined Antidiphtheritic Vaccine as a Perspective Preventive Measure of Corynebacteria diphtheriae Circulation Among the Population
title_full_unstemmed Anti-adhesive Strategy in Development of Combined Antidiphtheritic Vaccine as a Perspective Preventive Measure of Corynebacteria diphtheriae Circulation Among the Population
title_short Anti-adhesive Strategy in Development of Combined Antidiphtheritic Vaccine as a Perspective Preventive Measure of Corynebacteria diphtheriae Circulation Among the Population
title_sort anti adhesive strategy in development of combined antidiphtheritic vaccine as a perspective preventive measure of corynebacteria diphtheriae circulation among the population
topic diphtheria vaccines
c. diphtheriaе
diphtheria bacterial antigens
adhesion
electromagnetic radiation of microwave frequency
url https://detinf.elpub.ru/jour/article/view/167
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