Successful Intratracheal Treatment of Phage and Antibiotic Combination Therapy of a Multi-Drug Resistant <i>Pseudomonas aeruginosa</i> Murine Model

Successful Intratracheal Treatment of Phage and Antibiotic Combination Therapy of a Multi-Drug Resistant <i>Pseudomonas aeruginosa</i> Murine Model

Background: Pseudomonas aeruginosa (PsA) is a common etiology of bacteria-mediated lower respiratory tract infections, including pneumonia, hospital acquired pneumonia (HAP), and ventilator-associated pneumonia (VAP). Given the paucity of novel antibiotics in our foreseeable pipeline, developing nov...

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Bibliographic Details
Main Authors: Christopher Duplessis, Jonathan M. Warawa, Matthew B. Lawrenz, Matthew Henry, Biswajit Biswas
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Antibiotics
Subjects:
bacteriophage
<i>Pseudomonas aeruginosa</i>
pneumonia
multi-drug resistance
phage antibiotic synergy
intubation-mediated
Online Access:https://www.mdpi.com/2079-6382/10/8/946

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