Genetic risk for severe COVID‐19 correlates with lower inflammatory marker levels in a SARS‐CoV‐2‐negative cohort

Genetic risk for severe COVID‐19 correlates with lower inflammatory marker levels in a SARS‐CoV‐2‐negative cohort

Abstract Objectives It remains unknown how inflammatory marker levels differ amongst individuals susceptible to coronavirus disease 2019 (COVID‐19), prior to severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and the onset of the cytokine storm. We used genetic risk scores to mod...

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Bibliographic Details
Main Authors: Timothy R Powell, Matthew Hotopf, Stephani L Hatch, Gerome Breen, Rodrigo R R Duarte, Douglas F Nixon
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Clinical & Translational Immunology
Subjects:
COVID‐19
genetic risk
IFN‐γ
inflammation
SARS‐CoV‐2
TNF‐α
Online Access:https://doi.org/10.1002/cti2.1292

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