A case series from a single family of familial retinal arteriolar tortuosity with common history of sudden visual loss

Purpose: To report family members with familial retinal arteriolar tortuosity (FRAT) identified after sudden visual loss. Observations: A 15-year-old boy had sudden visual loss in his left eye while playing on a horizontal bar. He was referred to Nagoya City University Hospital from an eye clinic. T...

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Main Authors: Tomohiro Obayashi, Aki Kato, Harumitsu Suzuki, Kei Ohashi, Munenori Yoshida, Yu Shibata, Yuichiro Ogura, Tsutomu Yasukawa
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:American Journal of Ophthalmology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2451993621002395
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author Tomohiro Obayashi
Aki Kato
Harumitsu Suzuki
Kei Ohashi
Munenori Yoshida
Yu Shibata
Yuichiro Ogura
Tsutomu Yasukawa
author_facet Tomohiro Obayashi
Aki Kato
Harumitsu Suzuki
Kei Ohashi
Munenori Yoshida
Yu Shibata
Yuichiro Ogura
Tsutomu Yasukawa
author_sort Tomohiro Obayashi
collection DOAJ
description Purpose: To report family members with familial retinal arteriolar tortuosity (FRAT) identified after sudden visual loss. Observations: A 15-year-old boy had sudden visual loss in his left eye while playing on a horizontal bar. He was referred to Nagoya City University Hospital from an eye clinic. The ophthalmologic examination showed retinal hemorrhage bilaterally. His best-corrected visual acuity (BCVA) was 20/17 in the right eye and 20/67 in the left eye. Bilateral retinal arteriolar tortuosity as well as retinal hemorrhage was seen. Since his mother with 54 years of age also had a history of retinal hemorrhage that improved spontaneously, fundus examination was performed, revealing tortuosity of the retinal arterioles. Consequently, the patient and his mother were diagnosed as FRAT. He was followed without intervention. Retinal hemorrhage gradually decreased and resolved after 3 months. The BCVA of his left eye gradually improved and reached 20/20 after 1 year. Conclusions and importance: In this case, the family history was very useful for early diagnosis. Immediate and accurate diagnosis allowed the patient to be followed without intervention and achieve subsequent resolution of retinal hemorrhage and improved vision. FRAT should be considered in cases of sub-internal limiting membrane hemorrhages in young patients even in the presence of discrete retinal arteriolar tortuosity.
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spelling doaj.art-ab9b720c49764442aa00b03f633c4abe2022-12-21T23:37:54ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362021-12-0124101230A case series from a single family of familial retinal arteriolar tortuosity with common history of sudden visual lossTomohiro Obayashi0Aki Kato1Harumitsu Suzuki2Kei Ohashi3Munenori Yoshida4Yu Shibata5Yuichiro Ogura6Tsutomu Yasukawa7Department of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, JapanDepartment of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan; Corresponding author. Department of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi, 467-8601, Japan.Suzuki Eye Clinic Midori, Nagoya, Aichi, JapanDepartment of Pediatrics and Neonatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, JapanDepartment of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, JapanDepartment of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, JapanDepartment of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, JapanDepartment of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, JapanPurpose: To report family members with familial retinal arteriolar tortuosity (FRAT) identified after sudden visual loss. Observations: A 15-year-old boy had sudden visual loss in his left eye while playing on a horizontal bar. He was referred to Nagoya City University Hospital from an eye clinic. The ophthalmologic examination showed retinal hemorrhage bilaterally. His best-corrected visual acuity (BCVA) was 20/17 in the right eye and 20/67 in the left eye. Bilateral retinal arteriolar tortuosity as well as retinal hemorrhage was seen. Since his mother with 54 years of age also had a history of retinal hemorrhage that improved spontaneously, fundus examination was performed, revealing tortuosity of the retinal arterioles. Consequently, the patient and his mother were diagnosed as FRAT. He was followed without intervention. Retinal hemorrhage gradually decreased and resolved after 3 months. The BCVA of his left eye gradually improved and reached 20/20 after 1 year. Conclusions and importance: In this case, the family history was very useful for early diagnosis. Immediate and accurate diagnosis allowed the patient to be followed without intervention and achieve subsequent resolution of retinal hemorrhage and improved vision. FRAT should be considered in cases of sub-internal limiting membrane hemorrhages in young patients even in the presence of discrete retinal arteriolar tortuosity.http://www.sciencedirect.com/science/article/pii/S2451993621002395Familial retinal arteriolar tortuosityRetinal vascular tortuosityRetinal hemorrhagesCOL4A1
spellingShingle Tomohiro Obayashi
Aki Kato
Harumitsu Suzuki
Kei Ohashi
Munenori Yoshida
Yu Shibata
Yuichiro Ogura
Tsutomu Yasukawa
A case series from a single family of familial retinal arteriolar tortuosity with common history of sudden visual loss
American Journal of Ophthalmology Case Reports
Familial retinal arteriolar tortuosity
Retinal vascular tortuosity
Retinal hemorrhages
COL4A1
title A case series from a single family of familial retinal arteriolar tortuosity with common history of sudden visual loss
title_full A case series from a single family of familial retinal arteriolar tortuosity with common history of sudden visual loss
title_fullStr A case series from a single family of familial retinal arteriolar tortuosity with common history of sudden visual loss
title_full_unstemmed A case series from a single family of familial retinal arteriolar tortuosity with common history of sudden visual loss
title_short A case series from a single family of familial retinal arteriolar tortuosity with common history of sudden visual loss
title_sort case series from a single family of familial retinal arteriolar tortuosity with common history of sudden visual loss
topic Familial retinal arteriolar tortuosity
Retinal vascular tortuosity
Retinal hemorrhages
COL4A1
url http://www.sciencedirect.com/science/article/pii/S2451993621002395
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