miRNA Profiles of Monocyte-Lineage Cells Are Consistent with Complicated Roles in HIV-1 Restriction

miRNA Profiles of Monocyte-Lineage Cells Are Consistent with Complicated Roles in HIV-1 Restriction

Long-lived HIV-1 reservoirs include tissue macrophages. Monocyte-derived macrophages are more susceptible to infection and more permissive to HIV-1 replication than monocytes for reasons that may include the effects of different populations of miRNAs in these two cell classes. Specifically, miRs-28-...

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Bibliographic Details
Main Authors: Janice E. Clements, Jeanne M. Sisk, Kenneth W. Witwer
Format: Article
Language:English
Published: MDPI AG 2012-09-01
Series:Viruses
Subjects:
microRNA
HIV-1
monocyte
macrophage
profiling
antiviral
Online Access:http://www.mdpi.com/1999-4915/4/10/1844

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