Subthreshold Micropulse Laser for Long-Lasting Submacular Fluid after Rhegmatogeous Retinal Detachment Surgery
Abstract Purpose: To assess the safety and efficacy of subthreshold micropulse laser (SML) photo-stimulation in the management of persistent subfoveal fluid (PSF) after surgery for rhegmatogenous retinal detachment (RRD). Methods: In this pilot study, 11 eyes of 11 patients (8 men, 3 women) with lon...
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| Format: | Article |
| Language: | English |
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Knowledge E
2022-08-01
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| Series: | Journal of Ophthalmic & Vision Research |
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| Online Access: | https://doi.org/10.18502/jovr.v17i3.11577 |
| _version_ | 1811244525195100160 |
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| author | Giulia Esposti Pier Luigi Esposti Francesco Costantino Dario Zappalà Antonio Pinna Mario Fruschelli |
| author_facet | Giulia Esposti Pier Luigi Esposti Francesco Costantino Dario Zappalà Antonio Pinna Mario Fruschelli |
| author_sort | Giulia Esposti |
| collection | DOAJ |
| description | Abstract Purpose: To assess the safety and efficacy of subthreshold micropulse laser (SML) photo-stimulation in the management of persistent subfoveal fluid (PSF) after surgery for rhegmatogenous retinal detachment (RRD). Methods: In this pilot study, 11 eyes of 11 patients (8 men, 3 women) with long-lasting (12–18 months) PSF after surgery for RRD were evaluated before and after photostimulation with subthreshold micropulse yellow laser. Ophthalmic examination included best-corrected visual acuity (BCVA), Amsler grid test, ophthalmoscopy, autofluorescence (AF), and optical coherence tomography (OCT) with measurement of central point foveal thickness (CPFT). Primary outcome was subfoveal fluid resolution and secondary outcome was BCVA improvement. Results: The mean CPFT and BCVA were, respectively, 436.8 ± 28.8 μm and 0.25 ± 0.1 µm decimal equivalent (DE) before photostimulation and 278 ± 54.4 μm and 0.57 ± 0.2 µm DE after photostimulation, a statistically significant difference (P < 0.001). Nine (81.8%) eyes showed improved BCVA, disappearance of macular detachment on ophthalmoscopy, reduced retinal pigment epithelium distress on AF, and restored macular profile with no neuroretinal alterations on OCT scans. Conclusion: Although PSF after RRD surgery is often a self-limiting disease, our results suggest that SML photostimulation may be effective and safe in patients with clinically significant long-lasting PSF. Larger case–control studies are necessary to confirm these results. |
| first_indexed | 2024-04-12T14:26:36Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 2008-2010 2008-322X |
| language | English |
| last_indexed | 2024-04-12T14:26:36Z |
| publishDate | 2022-08-01 |
| publisher | Knowledge E |
| record_format | Article |
| series | Journal of Ophthalmic & Vision Research |
| spelling | doaj.art-aba276df89be412a9207ca43d1effe712022-12-22T03:29:26ZengKnowledge EJournal of Ophthalmic & Vision Research2008-20102008-322X2022-08-0117339039610.18502/jovr.v17i3.11577jovr.v17i3.11577Subthreshold Micropulse Laser for Long-Lasting Submacular Fluid after Rhegmatogeous Retinal Detachment SurgeryGiulia Esposti0Pier Luigi Esposti1Francesco Costantino2Dario Zappalà3Antonio Pinna4Mario Fruschelli5 Studio Oculistico Esposti, Siena, Italy Studio Oculistico Esposti, Siena, Italy Graduate School of Ophthalmology, University of Siena, Siena, Italy Graduate School of Ophthalmology, University of Siena, Siena, Italy Department of Medical, Surgical, and Experimental Sciences, Ophthalmology Unit, University of Sassari, Sassari, Italy Dipartimento di Scienze Mediche Chirurgiche e Neuroscienze, University of Siena, Siena, ItalyAbstract Purpose: To assess the safety and efficacy of subthreshold micropulse laser (SML) photo-stimulation in the management of persistent subfoveal fluid (PSF) after surgery for rhegmatogenous retinal detachment (RRD). Methods: In this pilot study, 11 eyes of 11 patients (8 men, 3 women) with long-lasting (12–18 months) PSF after surgery for RRD were evaluated before and after photostimulation with subthreshold micropulse yellow laser. Ophthalmic examination included best-corrected visual acuity (BCVA), Amsler grid test, ophthalmoscopy, autofluorescence (AF), and optical coherence tomography (OCT) with measurement of central point foveal thickness (CPFT). Primary outcome was subfoveal fluid resolution and secondary outcome was BCVA improvement. Results: The mean CPFT and BCVA were, respectively, 436.8 ± 28.8 μm and 0.25 ± 0.1 µm decimal equivalent (DE) before photostimulation and 278 ± 54.4 μm and 0.57 ± 0.2 µm DE after photostimulation, a statistically significant difference (P < 0.001). Nine (81.8%) eyes showed improved BCVA, disappearance of macular detachment on ophthalmoscopy, reduced retinal pigment epithelium distress on AF, and restored macular profile with no neuroretinal alterations on OCT scans. Conclusion: Although PSF after RRD surgery is often a self-limiting disease, our results suggest that SML photostimulation may be effective and safe in patients with clinically significant long-lasting PSF. Larger case–control studies are necessary to confirm these results.https://doi.org/10.18502/jovr.v17i3.11577optical coherence tomographyretinal pigment epitheliumrhegmatogenous retinal detachmentsubretinal fluidsubthreshold micropulse laser |
| spellingShingle | Giulia Esposti Pier Luigi Esposti Francesco Costantino Dario Zappalà Antonio Pinna Mario Fruschelli Subthreshold Micropulse Laser for Long-Lasting Submacular Fluid after Rhegmatogeous Retinal Detachment Surgery Journal of Ophthalmic & Vision Research optical coherence tomography retinal pigment epithelium rhegmatogenous retinal detachment subretinal fluid subthreshold micropulse laser |
| title | Subthreshold Micropulse Laser for Long-Lasting Submacular Fluid after Rhegmatogeous Retinal Detachment Surgery |
| title_full | Subthreshold Micropulse Laser for Long-Lasting Submacular Fluid after Rhegmatogeous Retinal Detachment Surgery |
| title_fullStr | Subthreshold Micropulse Laser for Long-Lasting Submacular Fluid after Rhegmatogeous Retinal Detachment Surgery |
| title_full_unstemmed | Subthreshold Micropulse Laser for Long-Lasting Submacular Fluid after Rhegmatogeous Retinal Detachment Surgery |
| title_short | Subthreshold Micropulse Laser for Long-Lasting Submacular Fluid after Rhegmatogeous Retinal Detachment Surgery |
| title_sort | subthreshold micropulse laser for long lasting submacular fluid after rhegmatogeous retinal detachment surgery |
| topic | optical coherence tomography retinal pigment epithelium rhegmatogenous retinal detachment subretinal fluid subthreshold micropulse laser |
| url | https://doi.org/10.18502/jovr.v17i3.11577 |
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