Noninvasive imaging of tumor hypoxia after nanoparticle-mediated tumor vascular disruption.

We have previously demonstrated that endothelial targeting of gold nanoparticles followed by external beam irradiation can cause specific tumor vascular disruption in mouse models of cancer. The induced vascular damage may lead to changes in tumor physiology, including tumor hypoxia, thereby comprom...

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Bibliographic Details
Main Authors: Needa A Virani, Olivia J Kelada, Sijumon Kunjachan, Alexandre Detappe, Jihun Kwon, Jennifer Hayashi, Ana Vazquez-Pagan, Douglas E Biancur, Thomas Ireland, Rajiv Kumar, Srinivas Sridhar, G Mike Makrigiorgos, Ross I Berbeco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0236245

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