Fluorinated or brominated meta‐diamides as the new scaffolds for the treatment of rice bacterial leaf blight
Abstract Rice is the main calorie source and stable food for half of the global population worldwide, while the rice bacterial leaf blight has been one of the main challenges to rice yields and quality. Herein, we revealed the novel scaffolds, fluorinated or brominated meta‐diamides (F1–F44), for tr...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-05-01
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| Series: | Food and Energy Security |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/fes3.449 |
| _version_ | 1797821233544298496 |
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| author | Shengxin Guo Feng He Wei Zhang Ya Wang Lijiao Yu Jian Wu |
| author_facet | Shengxin Guo Feng He Wei Zhang Ya Wang Lijiao Yu Jian Wu |
| author_sort | Shengxin Guo |
| collection | DOAJ |
| description | Abstract Rice is the main calorie source and stable food for half of the global population worldwide, while the rice bacterial leaf blight has been one of the main challenges to rice yields and quality. Herein, we revealed the novel scaffolds, fluorinated or brominated meta‐diamides (F1–F44), for treating the rice bacterial leaf bright for the first time. The major findings are as follows: (i) based on the different methods, fluorinated meta‐diamides and brominated meta‐diamides were obtained, respectively, and the latter has rarely been reported; (ii) fluorinated meta‐diamide F17 showed a protection activity of 51.3% and a curative activity of 48.7% against the rice bacterial leaf blight caused by the bacteria Xanthomonas oryzae pv. oryzae (Xoo), which were better than those of used bactericides. Scanning electron microscopy suggested that F17 may deform and rupture Xoo; and (iii) the majority of brominated meta‐diamides were more active than corresponding fluorinated meta‐diamides, which revealed the antibacterial activity of brominated meta‐diamides for the first time. The present work is expected to provide new ideas for meta‐diamides for treating rice bacterial leaf blight. |
| first_indexed | 2024-03-13T09:49:47Z |
| format | Article |
| id | doaj.art-aba2cbdaf64e4a0cbb05f1a028e016c2 |
| institution | Directory Open Access Journal |
| issn | 2048-3694 |
| language | English |
| last_indexed | 2024-03-13T09:49:47Z |
| publishDate | 2023-05-01 |
| publisher | Wiley |
| record_format | Article |
| series | Food and Energy Security |
| spelling | doaj.art-aba2cbdaf64e4a0cbb05f1a028e016c22023-05-24T14:36:38ZengWileyFood and Energy Security2048-36942023-05-01123n/an/a10.1002/fes3.449Fluorinated or brominated meta‐diamides as the new scaffolds for the treatment of rice bacterial leaf blightShengxin Guo0Feng He1Wei Zhang2Ya Wang3Lijiao Yu4Jian Wu5National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education Guizhou University Guiyang ChinaNational Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education Guizhou University Guiyang ChinaNational Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education Guizhou University Guiyang ChinaNational Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education Guizhou University Guiyang ChinaNational Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education Guizhou University Guiyang ChinaNational Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education Guizhou University Guiyang ChinaAbstract Rice is the main calorie source and stable food for half of the global population worldwide, while the rice bacterial leaf blight has been one of the main challenges to rice yields and quality. Herein, we revealed the novel scaffolds, fluorinated or brominated meta‐diamides (F1–F44), for treating the rice bacterial leaf bright for the first time. The major findings are as follows: (i) based on the different methods, fluorinated meta‐diamides and brominated meta‐diamides were obtained, respectively, and the latter has rarely been reported; (ii) fluorinated meta‐diamide F17 showed a protection activity of 51.3% and a curative activity of 48.7% against the rice bacterial leaf blight caused by the bacteria Xanthomonas oryzae pv. oryzae (Xoo), which were better than those of used bactericides. Scanning electron microscopy suggested that F17 may deform and rupture Xoo; and (iii) the majority of brominated meta‐diamides were more active than corresponding fluorinated meta‐diamides, which revealed the antibacterial activity of brominated meta‐diamides for the first time. The present work is expected to provide new ideas for meta‐diamides for treating rice bacterial leaf blight.https://doi.org/10.1002/fes3.449brominatedfluorinatedmeta‐diamidesnew scaffoldsrice bacterial leaf blight |
| spellingShingle | Shengxin Guo Feng He Wei Zhang Ya Wang Lijiao Yu Jian Wu Fluorinated or brominated meta‐diamides as the new scaffolds for the treatment of rice bacterial leaf blight Food and Energy Security brominated fluorinated meta‐diamides new scaffolds rice bacterial leaf blight |
| title | Fluorinated or brominated meta‐diamides as the new scaffolds for the treatment of rice bacterial leaf blight |
| title_full | Fluorinated or brominated meta‐diamides as the new scaffolds for the treatment of rice bacterial leaf blight |
| title_fullStr | Fluorinated or brominated meta‐diamides as the new scaffolds for the treatment of rice bacterial leaf blight |
| title_full_unstemmed | Fluorinated or brominated meta‐diamides as the new scaffolds for the treatment of rice bacterial leaf blight |
| title_short | Fluorinated or brominated meta‐diamides as the new scaffolds for the treatment of rice bacterial leaf blight |
| title_sort | fluorinated or brominated meta diamides as the new scaffolds for the treatment of rice bacterial leaf blight |
| topic | brominated fluorinated meta‐diamides new scaffolds rice bacterial leaf blight |
| url | https://doi.org/10.1002/fes3.449 |
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