Molecular Influence of the ATM Protein in the Treatment of Human Cells with Different Radioprotective Drugs: Comparisons between Antioxidative and Pro-Episkevic Strategies

Molecular Influence of the ATM Protein in the Treatment of Human Cells with Different Radioprotective Drugs: Comparisons between Antioxidative and Pro-Episkevic Strategies

The radiation protection strategy with chemical agents has long been based on an antioxidative approach consisting in reducing the number of radical oxygen and nitrogen species responsible for the formation of the radiation-induced (RI) DNA damage, notably the DNA double-strand breaks (DSB), whose s...

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Bibliographic Details
Main Authors: Juliette Restier-Verlet, Michel Drouet, Pauline Pras, Mélanie L. Ferlazzo, Adeline Granzotto, Laurène Sonzogni, Joëlle Al-Choboq, Laura El Nachef, Sabine François, Michel Bourguignon, Nicolas Foray
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biomolecules
Subjects:
radioprotectors
N-acetylcysteine
amifostine
statin
bisphosphonates
ATM
Online Access:https://www.mdpi.com/2218-273X/13/3/524

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