Exosomes from SIRT1-Overexpressing ADSCs Restore Cardiac Function by Improving Angiogenic Function of EPCs

Exosomes from SIRT1-Overexpressing ADSCs Restore Cardiac Function by Improving Angiogenic Function of EPCs

Acute myocardial infarction (AMI) is one of the leading causes of mortality in cardiovascular diseases. The aim of this study was to investigate whether exosomes from Sirtuin 1 (SIRT1)-overexpressing adipose-derived stem cells (ADSCs) had a protective effect on AMI. The expression of C-X-C chemokine...

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Bibliographic Details
Main Authors: Hui Huang, Zhenxing Xu, Yuan Qi, Wei Zhang, Chenjun Zhang, Mei Jiang, Shengqiong Deng, Hairong Wang
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
acute myocardial infarction
Sirtuin 1
adipose-tissue-derived stem cells
exosomes
Nrf2
chemokine receptor CXCR7
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120301967

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