Efficacy of visceral fat estimation by dual bioelectrical impedance analysis in detecting cardiovascular risk factors in patients with type 2 diabetes
Abstract Background Visceral fat area (VFA) is a good surrogate marker of obesity-related disorders, such as hypertension, dyslipidemia and glucose intolerance. Although estimating the VFA by X-ray computed tomography (CT) is the primary index for visceral obesity, it is expensive and requires invas...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-10-01
|
| Series: | Cardiovascular Diabetology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12933-019-0941-y |
| _version_ | 1818256272685793280 |
|---|---|
| author | Yoko Omura-Ohata Cheol Son Hisashi Makino Ryo Koezuka Mayu Tochiya Tamiko Tamanaha Ichiro Kishimoto Kiminori Hosoda |
| author_facet | Yoko Omura-Ohata Cheol Son Hisashi Makino Ryo Koezuka Mayu Tochiya Tamiko Tamanaha Ichiro Kishimoto Kiminori Hosoda |
| author_sort | Yoko Omura-Ohata |
| collection | DOAJ |
| description | Abstract Background Visceral fat area (VFA) is a good surrogate marker of obesity-related disorders, such as hypertension, dyslipidemia and glucose intolerance. Although estimating the VFA by X-ray computed tomography (CT) is the primary index for visceral obesity, it is expensive and requires invasive radiation exposure. Dual bioelectrical impedance analysis (BIA) is a simple and reliable method to estimate VFA; however, the clinical usefulness of dual BIA remains unclear in patients with type 2 diabetes (T2D). Methods We estimated the VFAs by dual BIA and CT in 98 patients with T2D and assessed anthropometric parameters, blood test results, and the presence of comorbid hypertension and dyslipidemia. We compared the correlation between the VFAs examined by dual BIA and CT. Furthermore, we performed the receiver operating characteristic (ROC) analyses for the VFAs to detect the presence of comorbid hypertension and/or dyslipidemia with T2D, which are major comorbidities of visceral obesity, and estimated the area under the curve (AUC). Results The measurement error between the VFAs by dual BIA and CT was significantly higher among patients with brain natriuretic peptide (BNP) ≥ 100 pg/mL than those with BNP < 100 pg/mL (39.2% ± 31.1% vs. 24.1% ± 18.6%, P < 0.05). After excluding patients with BNP ≥ 100 pg/mL, the VFA by dual BIA significantly correlated with the VFA by CT (r = 0.917; P < 0.0001). The AUC in the ROC analysis for the VFA by dual BIA to detect the presence of comorbid hypertension and/or dyslipidemia with T2D was almost equivalent to that for the VFA by CT. Conclusions In patients with T2D without elevated BNP > 100 pg/mL as indicator for fluid accumulation interfering with BIA, estimation of the VFA by dual BIA significantly correlated with that by CT and also detected comorbid hypertension and/or dyslipidemia with T2D equivalent to those detected by CT. Hence, dual BIA could be an alternative to CT as a standard method for estimating the VFA in patients with diabetes. |
| first_indexed | 2024-12-12T17:25:07Z |
| format | Article |
| id | doaj.art-abac68cd722f47c38163a96cd2e5819e |
| institution | Directory Open Access Journal |
| issn | 1475-2840 |
| language | English |
| last_indexed | 2024-12-12T17:25:07Z |
| publishDate | 2019-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Cardiovascular Diabetology |
| spelling | doaj.art-abac68cd722f47c38163a96cd2e5819e2022-12-22T00:17:33ZengBMCCardiovascular Diabetology1475-28402019-10-011811810.1186/s12933-019-0941-yEfficacy of visceral fat estimation by dual bioelectrical impedance analysis in detecting cardiovascular risk factors in patients with type 2 diabetesYoko Omura-Ohata0Cheol Son1Hisashi Makino2Ryo Koezuka3Mayu Tochiya4Tamiko Tamanaha5Ichiro Kishimoto6Kiminori Hosoda7Division of Diabetes and Lipid Metabolism, National Cerebral and Cardiovascular CenterDivision of Diabetes and Lipid Metabolism, National Cerebral and Cardiovascular CenterDivision of Diabetes and Lipid Metabolism, National Cerebral and Cardiovascular CenterDivision of Diabetes and Lipid Metabolism, National Cerebral and Cardiovascular CenterDivision of Diabetes and Lipid Metabolism, National Cerebral and Cardiovascular CenterDivision of Diabetes and Lipid Metabolism, National Cerebral and Cardiovascular CenterDivision of Diabetes and Lipid Metabolism, National Cerebral and Cardiovascular CenterDivision of Diabetes and Lipid Metabolism, National Cerebral and Cardiovascular CenterAbstract Background Visceral fat area (VFA) is a good surrogate marker of obesity-related disorders, such as hypertension, dyslipidemia and glucose intolerance. Although estimating the VFA by X-ray computed tomography (CT) is the primary index for visceral obesity, it is expensive and requires invasive radiation exposure. Dual bioelectrical impedance analysis (BIA) is a simple and reliable method to estimate VFA; however, the clinical usefulness of dual BIA remains unclear in patients with type 2 diabetes (T2D). Methods We estimated the VFAs by dual BIA and CT in 98 patients with T2D and assessed anthropometric parameters, blood test results, and the presence of comorbid hypertension and dyslipidemia. We compared the correlation between the VFAs examined by dual BIA and CT. Furthermore, we performed the receiver operating characteristic (ROC) analyses for the VFAs to detect the presence of comorbid hypertension and/or dyslipidemia with T2D, which are major comorbidities of visceral obesity, and estimated the area under the curve (AUC). Results The measurement error between the VFAs by dual BIA and CT was significantly higher among patients with brain natriuretic peptide (BNP) ≥ 100 pg/mL than those with BNP < 100 pg/mL (39.2% ± 31.1% vs. 24.1% ± 18.6%, P < 0.05). After excluding patients with BNP ≥ 100 pg/mL, the VFA by dual BIA significantly correlated with the VFA by CT (r = 0.917; P < 0.0001). The AUC in the ROC analysis for the VFA by dual BIA to detect the presence of comorbid hypertension and/or dyslipidemia with T2D was almost equivalent to that for the VFA by CT. Conclusions In patients with T2D without elevated BNP > 100 pg/mL as indicator for fluid accumulation interfering with BIA, estimation of the VFA by dual BIA significantly correlated with that by CT and also detected comorbid hypertension and/or dyslipidemia with T2D equivalent to those detected by CT. Hence, dual BIA could be an alternative to CT as a standard method for estimating the VFA in patients with diabetes.http://link.springer.com/article/10.1186/s12933-019-0941-yVisceral fatType 2 diabetesImpedanceCardiovascular risk factor |
| spellingShingle | Yoko Omura-Ohata Cheol Son Hisashi Makino Ryo Koezuka Mayu Tochiya Tamiko Tamanaha Ichiro Kishimoto Kiminori Hosoda Efficacy of visceral fat estimation by dual bioelectrical impedance analysis in detecting cardiovascular risk factors in patients with type 2 diabetes Cardiovascular Diabetology Visceral fat Type 2 diabetes Impedance Cardiovascular risk factor |
| title | Efficacy of visceral fat estimation by dual bioelectrical impedance analysis in detecting cardiovascular risk factors in patients with type 2 diabetes |
| title_full | Efficacy of visceral fat estimation by dual bioelectrical impedance analysis in detecting cardiovascular risk factors in patients with type 2 diabetes |
| title_fullStr | Efficacy of visceral fat estimation by dual bioelectrical impedance analysis in detecting cardiovascular risk factors in patients with type 2 diabetes |
| title_full_unstemmed | Efficacy of visceral fat estimation by dual bioelectrical impedance analysis in detecting cardiovascular risk factors in patients with type 2 diabetes |
| title_short | Efficacy of visceral fat estimation by dual bioelectrical impedance analysis in detecting cardiovascular risk factors in patients with type 2 diabetes |
| title_sort | efficacy of visceral fat estimation by dual bioelectrical impedance analysis in detecting cardiovascular risk factors in patients with type 2 diabetes |
| topic | Visceral fat Type 2 diabetes Impedance Cardiovascular risk factor |
| url | http://link.springer.com/article/10.1186/s12933-019-0941-y |
| work_keys_str_mv | AT yokoomuraohata efficacyofvisceralfatestimationbydualbioelectricalimpedanceanalysisindetectingcardiovascularriskfactorsinpatientswithtype2diabetes AT cheolson efficacyofvisceralfatestimationbydualbioelectricalimpedanceanalysisindetectingcardiovascularriskfactorsinpatientswithtype2diabetes AT hisashimakino efficacyofvisceralfatestimationbydualbioelectricalimpedanceanalysisindetectingcardiovascularriskfactorsinpatientswithtype2diabetes AT ryokoezuka efficacyofvisceralfatestimationbydualbioelectricalimpedanceanalysisindetectingcardiovascularriskfactorsinpatientswithtype2diabetes AT mayutochiya efficacyofvisceralfatestimationbydualbioelectricalimpedanceanalysisindetectingcardiovascularriskfactorsinpatientswithtype2diabetes AT tamikotamanaha efficacyofvisceralfatestimationbydualbioelectricalimpedanceanalysisindetectingcardiovascularriskfactorsinpatientswithtype2diabetes AT ichirokishimoto efficacyofvisceralfatestimationbydualbioelectricalimpedanceanalysisindetectingcardiovascularriskfactorsinpatientswithtype2diabetes AT kiminorihosoda efficacyofvisceralfatestimationbydualbioelectricalimpedanceanalysisindetectingcardiovascularriskfactorsinpatientswithtype2diabetes |