Cerebrospinal fluid endo-lysosomal proteins as potential biomarkers for Huntington's disease.

Cerebrospinal fluid endo-lysosomal proteins as potential biomarkers for Huntington's disease.

Molecular markers derived from cerebrospinal fluid (CSF) represent an accessible means of exploring the pathobiology of Huntington's disease (HD) in vivo. The endo-lysosomal/autophagy system is dysfunctional in HD, potentially contributing to disease pathogenesis and representing a potential ta...

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Bibliographic Details
Main Authors:	Alexander J Lowe, Simon Sjödin, Filipe B Rodrigues, Lauren M Byrne, Kaj Blennow, Rosanna Tortelli, Henrik Zetterberg, Edward J Wild
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2020-01-01
Series:	PLoS ONE
Online Access:	https://doi.org/10.1371/journal.pone.0233820

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