Synthesis of 6a,7b-dihydroxyvouacapan-17b-oic acid derivatives. Part IV: mannich base derivatives and its activities on the electrically stimulated Guinea-pig ileum preparation

Synthesis of 6a,7b-dihydroxyvouacapan-17b-oic acid derivatives. Part IV: mannich base derivatives and its activities on the electrically stimulated Guinea-pig ileum preparation

The furanditerpene 6alpha,7beta-dihydroxyvouacapan-17beta-oic acid (ADV, 1), isolated from Pterodon polygalaeflorus Benth fruits, presents analgesic activity in current rodent experimental models. With the aim to gather data for biological studies it were obtained six new amide derivatives substitut...

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Bibliographic Details
Main Authors: Belinelo Valdenir J., Reis Genuína T., Stefani Guglielmo M., Ferreira-Alves Dalton L., Piló-Veloso Dorila
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2002-01-01
Series:Journal of the Brazilian Chemical Society
Subjects:
furanditerpenes
vouacapanoids
Pterodon polygalaeflorus
analgesics
Mannich bases
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532002000600016

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