Postoperative atypical hemolytic uremic syndrome in nontransplant setting: A case report with review of literature

Atypical hemolytic uremic syndrome (aHUS) is a clinical diagnosis characterized by a triad of microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction. Postoperative aHUS in nontransplant patients is a rare entity. The proposed underlying mechanism is complement cascade dysregulati...

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Bibliographic Details
Main Authors: Anil Khetarpal, Vidhi Gupta, Urvershi Kotwal
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Global Journal of Transfusion Medicine
Subjects:
Online Access:http://www.gjtmonline.com/article.asp?issn=2468-8398;year=2018;volume=3;issue=1;spage=64;epage=67;aulast=Khetarpal
Description
Summary:Atypical hemolytic uremic syndrome (aHUS) is a clinical diagnosis characterized by a triad of microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction. Postoperative aHUS in nontransplant patients is a rare entity. The proposed underlying mechanism is complement cascade dysregulation. aHUS has high morbidity and mortality. Prompt intervention with early initiation of therapeutic plasma exchange helps in the hematological remission thus reducing morbidity.
ISSN:2468-8398
2455-8893