Total and Unbound Pharmacokinetics of Cefiderocol in Critically Ill Patients

Total and Unbound Pharmacokinetics of Cefiderocol in Critically Ill Patients

Background: Cefiderocol is a siderophore cephalosporin antibiotic active against Gram-negative bacteria, including extended-spectrum beta-lactamase and carbapenemase-producing strains. The pharmacokinetics of cefiderocol has been studied in healthy subjects and particularly in phase II and III studi...

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Bibliographic Details
Main Authors: Noël Zahr, Saik Urien, Benoit Llopis, Gaëlle Noé, Nadine Tissot, Kevin Bihan, Helga Junot, Clémence Marin, Bochra Mansour, Charles-Edouard Luyt, Alexandre Bleibtreu, Christian Funck-Brentano
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceutics
Subjects:
cefiderocol
pharmacokinetics
PK/PD
antibiotics
drug monitoring
Online Access:https://www.mdpi.com/1999-4923/14/12/2786

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