Efficacy and safety of artemether–lumefantrine as treatment for Plasmodium falciparum uncomplicated malaria in adult patients on efavirenz-based antiretroviral therapy in Zambia: an open label non-randomized interventional trial

Efficacy and safety of artemether–lumefantrine as treatment for Plasmodium falciparum uncomplicated malaria in adult patients on efavirenz-based antiretroviral therapy in Zambia: an open label non-randomized interventional trial

Abstract Background HIV-infected individuals on antiretroviral therapy (ART) require treatment with artemisinin-based combination therapy (ACT) when infected with malaria. Artemether–lumefantrine (AL) is the most commonly used ACT for treatment of falciparum malaria in Africa but there is limited ev...

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Bibliographic Details
Main Authors: Clifford G. Banda, Mike Chaponda, Mavuto Mukaka, Modest Mulenga, Sebastian Hachizovu, Jean B. Kabuya, Joyce Mulenga, Jay Sikalima, Linda Kalilani-Phiri, Dianne J. Terlouw, Saye H. Khoo, David G. Lalloo, Victor Mwapasa
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Malaria Journal
Subjects:
Human immunodeficiency virus
Anti-retroviral drugs
Artemether–lumefantrine
Malaria
Drug–drug interactions
Online Access:http://link.springer.com/article/10.1186/s12936-019-2818-7

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