The clinical effectiveness and cost-effectiveness of testing for cytochrome P450 polymorphisms in patients with schizophrenia treated with antipsychotics: a systematic review and economic evaluation

The clinical effectiveness and cost-effectiveness of testing for cytochrome P450 polymorphisms in patients with schizophrenia treated with antipsychotics: a systematic review and economic evaluation

Objective: To determine whether testing for cytochrome P450 (CYP) polymorphisms in adults entering antipsychotic treatment for schizophrenia leads to improvement in outcomes, is useful in medical, personal or public health decision-making, and is a cost-effective use of health-care resources. Data s...

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Bibliographic Details
Main Authors: N Fleeman, C McLeod, A Bagust, S Beale, A Boland, Y Dundar, A Jorgensen, K Payne, M Pirmohamed, S Pushpakom, T Walley, P de Warren-Penny, R Dickson
Format: Article
Language:English
Published: NIHR Journals Library 2010-01-01
Series:Health Technology Assessment
Subjects:
cytochrome-p450-polymorphisms
schizophrenia
antipsychotics
genotyping
pharmacogenetic-testing
systematic-review
economic-evaluation
Online Access:https://doi.org/10.3310/hta14030

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