Identification of the transcription factor ZEB1 as a central component of the adipogenic gene regulatory network

Identification of the transcription factor ZEB1 as a central component of the adipogenic gene regulatory network

Adipose tissue is a key determinant of whole body metabolism and energy homeostasis. Unraveling the regulatory mechanisms underlying adipogenesis is therefore highly relevant from a biomedical perspective. Our current understanding of fat cell differentiation is centered on the transcriptional casca...

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Bibliographic Details
Main Authors: Carine Gubelmann, Petra C Schwalie, Sunil K Raghav, Eva Röder, Tenagne Delessa, Elke Kiehlmann, Sebastian M Waszak, Andrea Corsinotti, Gilles Udin, Wiebke Holcombe, Gottfried Rudofsky, Didier Trono, Christian Wolfrum, Bart Deplancke
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-08-01
Series:eLife
Subjects:
adipogenesis
zeb1
transcription factor screen
gene regulatory network
mesenchymal stem cell
Online Access:https://elifesciences.org/articles/03346

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