Deep Eutectic Solvents: Are They Safe?

Deep eutectic solvents (DESs) are a relatively new type of solvent that have attracted the attention of the scientific community due to their environmentally friendly properties and their versatility in many applications. Many possible DESs have been described and, thus, it is not easy to unequivoca...

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Main Authors: Laura Lomba, Mª Pilar Ribate, Estela Sangüesa, Julia Concha, M ª Pilar Garralaga, Diego Errazquin, Cristina B. García, Beatriz Giner
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/11/21/10061
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author Laura Lomba
Mª Pilar Ribate
Estela Sangüesa
Julia Concha
M ª Pilar Garralaga
Diego Errazquin
Cristina B. García
Beatriz Giner
author_facet Laura Lomba
Mª Pilar Ribate
Estela Sangüesa
Julia Concha
M ª Pilar Garralaga
Diego Errazquin
Cristina B. García
Beatriz Giner
author_sort Laura Lomba
collection DOAJ
description Deep eutectic solvents (DESs) are a relatively new type of solvent that have attracted the attention of the scientific community due to their environmentally friendly properties and their versatility in many applications. Many possible DESs have been described and, thus, it is not easy to unequivocally characterize and generalize their properties. This is especially important in the case of the (eco)toxicity information that can be found for these mixtures. In this review, we collect data on the human and environmental toxicity of DESs, with the aim of gathering and exploring the behavioral patterns of DESs. The toxicity data found were analyzed attending to different factors: hydrogen bond donors or acceptors that form part of the eutectic mixture, pH, and the presence of organic acids in the DES molar ratio of the components, or interactions with natural compounds. In the case of ecotoxicity, results generally depend on the biomodel studied, along with other factors that have been also revised. Finally, we also carried out a revision of the biodegradation of DESs.
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spelling doaj.art-abc862e1242e4ccd81745ba95b4948a62023-11-22T20:27:09ZengMDPI AGApplied Sciences2076-34172021-10-0111211006110.3390/app112110061Deep Eutectic Solvents: Are They Safe?Laura Lomba0Mª Pilar Ribate1Estela Sangüesa2Julia Concha3M ª Pilar Garralaga4Diego Errazquin5Cristina B. García6Beatriz Giner7Campus Facultad de Ciencias de la Salud, Farmacia, Universidad San Jorge, Autov A23 km 299, Villanueva de Gállego, 50830 Zaragoza, SpainCampus Facultad de Ciencias de la Salud, Farmacia, Universidad San Jorge, Autov A23 km 299, Villanueva de Gállego, 50830 Zaragoza, SpainCampus Facultad de Ciencias de la Salud, Farmacia, Universidad San Jorge, Autov A23 km 299, Villanueva de Gállego, 50830 Zaragoza, SpainCampus Facultad de Ciencias de la Salud, Farmacia, Universidad San Jorge, Autov A23 km 299, Villanueva de Gállego, 50830 Zaragoza, SpainCampus Facultad de Ciencias de la Salud, Farmacia, Universidad San Jorge, Autov A23 km 299, Villanueva de Gállego, 50830 Zaragoza, SpainCampus Facultad de Ciencias de la Salud, Farmacia, Universidad San Jorge, Autov A23 km 299, Villanueva de Gállego, 50830 Zaragoza, SpainCampus Facultad de Ciencias de la Salud, Farmacia, Universidad San Jorge, Autov A23 km 299, Villanueva de Gállego, 50830 Zaragoza, SpainCampus Facultad de Ciencias de la Salud, Farmacia, Universidad San Jorge, Autov A23 km 299, Villanueva de Gállego, 50830 Zaragoza, SpainDeep eutectic solvents (DESs) are a relatively new type of solvent that have attracted the attention of the scientific community due to their environmentally friendly properties and their versatility in many applications. Many possible DESs have been described and, thus, it is not easy to unequivocally characterize and generalize their properties. This is especially important in the case of the (eco)toxicity information that can be found for these mixtures. In this review, we collect data on the human and environmental toxicity of DESs, with the aim of gathering and exploring the behavioral patterns of DESs. The toxicity data found were analyzed attending to different factors: hydrogen bond donors or acceptors that form part of the eutectic mixture, pH, and the presence of organic acids in the DES molar ratio of the components, or interactions with natural compounds. In the case of ecotoxicity, results generally depend on the biomodel studied, along with other factors that have been also revised. Finally, we also carried out a revision of the biodegradation of DESs.https://www.mdpi.com/2076-3417/11/21/10061deep eutectic solvents (DESs)toxicityecotoxicity
spellingShingle Laura Lomba
Mª Pilar Ribate
Estela Sangüesa
Julia Concha
M ª Pilar Garralaga
Diego Errazquin
Cristina B. García
Beatriz Giner
Deep Eutectic Solvents: Are They Safe?
Applied Sciences
deep eutectic solvents (DESs)
toxicity
ecotoxicity
title Deep Eutectic Solvents: Are They Safe?
title_full Deep Eutectic Solvents: Are They Safe?
title_fullStr Deep Eutectic Solvents: Are They Safe?
title_full_unstemmed Deep Eutectic Solvents: Are They Safe?
title_short Deep Eutectic Solvents: Are They Safe?
title_sort deep eutectic solvents are they safe
topic deep eutectic solvents (DESs)
toxicity
ecotoxicity
url https://www.mdpi.com/2076-3417/11/21/10061
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