A Novel In Vivo Active Pemphigus Model Targeting Desmoglein1 and Desmoglein3: A Tool Representing All Pemphigus Variants

A Novel In Vivo Active Pemphigus Model Targeting Desmoglein1 and Desmoglein3: A Tool Representing All Pemphigus Variants

<b>Background:</b> Pemphigus is a life-threatening blistering autoimmune disease. Several forms, characterized by the presence of autoantibodies against different autoantigens, have been described. In Pemphigus Vulgaris (PV), autoantibodies target the cadherin Desmoglein 3 (DSG3), while...

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Bibliographic Details
Main Authors: Roberta Lotti, Claudio Giacinto Atene, Emma Dorotea Zanfi, Matteo Bertesi, Carlo Pincelli, Tommaso Zanocco-Marani
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Biology
Subjects:
autoimmune disease
skin models
pemphigus
desmoglein
Online Access:https://www.mdpi.com/2079-7737/12/5/702

Internet

https://www.mdpi.com/2079-7737/12/5/702

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