Recent advances in the role of proinflammatory cytokines in the pathogenesis of idiopathic optic neuritis
Optic neuritis(ON), which is the blinding optic nerve diseases that the young and middle-aged population are most susceptible to, is an optic neuropathy caused by various factors. Idiopathic optic neuritis(ION)occurs most frequently asmultiple sclerosis related optic neuritis(MS-ON)and neuromyelitis...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2020-09-01
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| Series: | Guoji Yanke Zazhi |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/cn_publish/2020/9/202009015.pdf |
| _version_ | 1818335968984301568 |
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| author | Ying-Xin Zi Ming Jin |
| author_facet | Ying-Xin Zi Ming Jin |
| author_sort | Ying-Xin Zi |
| collection | DOAJ |
| description | Optic neuritis(ON), which is the blinding optic nerve diseases that the young and middle-aged population are most susceptible to, is an optic neuropathy caused by various factors. Idiopathic optic neuritis(ION)occurs most frequently asmultiple sclerosis related optic neuritis(MS-ON)and neuromyelitis optica related optic neuritis(NMO-ON). ION has the characteristics of acute onset, easy recurrence, and serious dysfunction. Inflammation is an important mechanism of ION. By mediating inflammatory responses and participating in immune responses, proinflammatory cytokines, as one of cytokines which is a general term for a class of small molecule soluble peptides that regulate the immune system, have caused widespread concern in the pathogenesis of ION. This article reviews and discusses researches on the pathogenesis of proinflammatory cytokines-mediated ION at home and abroad in an effort to promote an in-depth study of the pathogenesis, diagnosis and treatment of ION. |
| first_indexed | 2024-12-13T14:31:52Z |
| format | Article |
| id | doaj.art-abcbc619ef2d475a8636681928751edf |
| institution | Directory Open Access Journal |
| issn | 1672-5123 1672-5123 |
| language | English |
| last_indexed | 2024-12-13T14:31:52Z |
| publishDate | 2020-09-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-abcbc619ef2d475a8636681928751edf2022-12-21T23:41:48ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232020-09-012091543154610.3980/j.issn.1672-5123.2020.9.15Recent advances in the role of proinflammatory cytokines in the pathogenesis of idiopathic optic neuritisYing-Xin Zi0Ming Jin1Beijing University of Chinese Medicine, Beijing 100029, China; Department of Ophthalmology, China-Japan Friendship Hospital, Beijing 100029, ChinaDepartment of Ophthalmology, China-Japan Friendship Hospital, Beijing 100029, ChinaOptic neuritis(ON), which is the blinding optic nerve diseases that the young and middle-aged population are most susceptible to, is an optic neuropathy caused by various factors. Idiopathic optic neuritis(ION)occurs most frequently asmultiple sclerosis related optic neuritis(MS-ON)and neuromyelitis optica related optic neuritis(NMO-ON). ION has the characteristics of acute onset, easy recurrence, and serious dysfunction. Inflammation is an important mechanism of ION. By mediating inflammatory responses and participating in immune responses, proinflammatory cytokines, as one of cytokines which is a general term for a class of small molecule soluble peptides that regulate the immune system, have caused widespread concern in the pathogenesis of ION. This article reviews and discusses researches on the pathogenesis of proinflammatory cytokines-mediated ION at home and abroad in an effort to promote an in-depth study of the pathogenesis, diagnosis and treatment of ION.http://ies.ijo.cn/cn_publish/2020/9/202009015.pdfproinflammatory cytokinesidiopathic optic neuritispathogenesis |
| spellingShingle | Ying-Xin Zi Ming Jin Recent advances in the role of proinflammatory cytokines in the pathogenesis of idiopathic optic neuritis Guoji Yanke Zazhi proinflammatory cytokines idiopathic optic neuritis pathogenesis |
| title | Recent advances in the role of proinflammatory cytokines in the pathogenesis of idiopathic optic neuritis |
| title_full | Recent advances in the role of proinflammatory cytokines in the pathogenesis of idiopathic optic neuritis |
| title_fullStr | Recent advances in the role of proinflammatory cytokines in the pathogenesis of idiopathic optic neuritis |
| title_full_unstemmed | Recent advances in the role of proinflammatory cytokines in the pathogenesis of idiopathic optic neuritis |
| title_short | Recent advances in the role of proinflammatory cytokines in the pathogenesis of idiopathic optic neuritis |
| title_sort | recent advances in the role of proinflammatory cytokines in the pathogenesis of idiopathic optic neuritis |
| topic | proinflammatory cytokines idiopathic optic neuritis pathogenesis |
| url | http://ies.ijo.cn/cn_publish/2020/9/202009015.pdf |
| work_keys_str_mv | AT yingxinzi recentadvancesintheroleofproinflammatorycytokinesinthepathogenesisofidiopathicopticneuritis AT mingjin recentadvancesintheroleofproinflammatorycytokinesinthepathogenesisofidiopathicopticneuritis |