Synthesis of Micheliolide Derivatives and Their Activities against AML Progenitor Cells

Synthesis of Micheliolide Derivatives and Their Activities against AML Progenitor Cells

Micheliolide (MCL) derivatives with etherification or esterification of the hydroxyl group at the C4 position were synthesized and evaluated for their activities against different acute myelogenous leukemia (AML) cell lines. These derivatives demonstrated comparable activities against AML cell lines...

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Bibliographic Details
Main Authors: Yue Chen, Quan Zhang, Jing Long, Qian-Qian Shi, Ya-Hui Ding, Wei-Wei Ma
Format: Article
Language:English
Published: MDPI AG 2013-05-01
Series:Molecules
Subjects:
leukemia progenitor cell
micheliolide
KG-1a
deriviative
sythesis
Online Access:http://www.mdpi.com/1420-3049/18/5/5980

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