Chitosan nanocapsules of tarragon essential oil with low cytotoxicity and long-lasting activity as a green nano-larvicide
Frequent use of synthetic larvicides has led to the development of resistance in many species of mosquitoes as well as risk of environmental pollution. Recently, encapsulating essential oils (EOs) in surfactants or polymers is being employed as an approach to control the volatility of EOs as green l...
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| Format: | Article |
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Nanoscience and Nanotechnology Research Center, University of Kashan
2019-10-01
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| Series: | Journal of Nanostructures |
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| Online Access: | http://jns.kashanu.ac.ir/article_99378_22693e523b65a0f927afb1dfd11c65e7.pdf |
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| author | Mahmoud Osanloo Mohammad Mehdi Sedaghat Hassan Sereshti Mahya Rahmani Farzaneh Saeedi Landi Amir Amani |
| author_facet | Mahmoud Osanloo Mohammad Mehdi Sedaghat Hassan Sereshti Mahya Rahmani Farzaneh Saeedi Landi Amir Amani |
| author_sort | Mahmoud Osanloo |
| collection | DOAJ |
| description | Frequent use of synthetic larvicides has led to the development of resistance in many species of mosquitoes as well as risk of environmental pollution. Recently, encapsulating essential oils (EOs) in surfactants or polymers is being employed as an approach to control the volatility of EOs as green larvicides. In this research, components of tarragon (Artemisia dracunculus) essential oil were identified by GC-MS analysis. Forty-eight components were identified, with 5 major components including estragole (67.623%), cis-Ocimene (8.691%), beta-Ocimene Y (7.577%), Limonene (4.338%) and 3-Methoxy cinnam aldehyde (1.49%). Tarragon EO was encapsulated in chitosan nanocapsules using ionic gelation method and confirmed by FT-IR analysis. Encapsulation efficiency and size of the chitosan nanocapsules were determined 34.91 ± 2% and 203 ± 16 nm, respectively. For the first time, a long-lasting green larvicide was reported which remained active for 10 days, against Anopheles stephensi. Furthermore, cytotoxicity of the nanoformulation was found to be similar to that of temephos on human skin normal cells (HFFF2). This nanoformulation can be a good alternative for synthetic larvicides due to its long-lasting activity, proper effectiveness and also its green constituents. |
| first_indexed | 2024-12-19T22:53:04Z |
| format | Article |
| id | doaj.art-abcf325782114e8a90e019f0b3c80288 |
| institution | Directory Open Access Journal |
| issn | 2251-7871 2251-788X |
| language | English |
| last_indexed | 2024-12-19T22:53:04Z |
| publishDate | 2019-10-01 |
| publisher | Nanoscience and Nanotechnology Research Center, University of Kashan |
| record_format | Article |
| series | Journal of Nanostructures |
| spelling | doaj.art-abcf325782114e8a90e019f0b3c802882022-12-21T20:02:44ZengNanoscience and Nanotechnology Research Center, University of KashanJournal of Nanostructures2251-78712251-788X2019-10-019472373510.22052/JNS.2019.04.01499378Chitosan nanocapsules of tarragon essential oil with low cytotoxicity and long-lasting activity as a green nano-larvicideMahmoud Osanloo0Mohammad Mehdi Sedaghat1Hassan Sereshti2Mahya Rahmani3Farzaneh Saeedi Landi4Amir Amani5Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Fasa University of Medical Sciences, Fasa, Iran.|Natural Products and Medicinal Plants Research Center, North Khorasan University of Medical Sciences, Bojnurd, IranDepartment of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.Department of Chemistry, Faculty of Science, University of Tehran, Tehran, Iran.Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.Natural Products and Medicinal Plants Research Center, North Khorasan University of Medical Sciences, Bojnurd, IranNatural Products and Medicinal Plants Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran | Medical Biomaterials Research Center, Tehran University of Medical Sciences, Tehran, Iran.Frequent use of synthetic larvicides has led to the development of resistance in many species of mosquitoes as well as risk of environmental pollution. Recently, encapsulating essential oils (EOs) in surfactants or polymers is being employed as an approach to control the volatility of EOs as green larvicides. In this research, components of tarragon (Artemisia dracunculus) essential oil were identified by GC-MS analysis. Forty-eight components were identified, with 5 major components including estragole (67.623%), cis-Ocimene (8.691%), beta-Ocimene Y (7.577%), Limonene (4.338%) and 3-Methoxy cinnam aldehyde (1.49%). Tarragon EO was encapsulated in chitosan nanocapsules using ionic gelation method and confirmed by FT-IR analysis. Encapsulation efficiency and size of the chitosan nanocapsules were determined 34.91 ± 2% and 203 ± 16 nm, respectively. For the first time, a long-lasting green larvicide was reported which remained active for 10 days, against Anopheles stephensi. Furthermore, cytotoxicity of the nanoformulation was found to be similar to that of temephos on human skin normal cells (HFFF2). This nanoformulation can be a good alternative for synthetic larvicides due to its long-lasting activity, proper effectiveness and also its green constituents.http://jns.kashanu.ac.ir/article_99378_22693e523b65a0f927afb1dfd11c65e7.pdflong lastinganopheles stephensitarragon essential oilchitosan nanocapsules and cytotoxicity |
| spellingShingle | Mahmoud Osanloo Mohammad Mehdi Sedaghat Hassan Sereshti Mahya Rahmani Farzaneh Saeedi Landi Amir Amani Chitosan nanocapsules of tarragon essential oil with low cytotoxicity and long-lasting activity as a green nano-larvicide Journal of Nanostructures long lasting anopheles stephensi tarragon essential oil chitosan nanocapsules and cytotoxicity |
| title | Chitosan nanocapsules of tarragon essential oil with low cytotoxicity and long-lasting activity as a green nano-larvicide |
| title_full | Chitosan nanocapsules of tarragon essential oil with low cytotoxicity and long-lasting activity as a green nano-larvicide |
| title_fullStr | Chitosan nanocapsules of tarragon essential oil with low cytotoxicity and long-lasting activity as a green nano-larvicide |
| title_full_unstemmed | Chitosan nanocapsules of tarragon essential oil with low cytotoxicity and long-lasting activity as a green nano-larvicide |
| title_short | Chitosan nanocapsules of tarragon essential oil with low cytotoxicity and long-lasting activity as a green nano-larvicide |
| title_sort | chitosan nanocapsules of tarragon essential oil with low cytotoxicity and long lasting activity as a green nano larvicide |
| topic | long lasting anopheles stephensi tarragon essential oil chitosan nanocapsules and cytotoxicity |
| url | http://jns.kashanu.ac.ir/article_99378_22693e523b65a0f927afb1dfd11c65e7.pdf |
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