eIF6 promotes the malignant progression of human hepatocellular carcinoma via the mTOR signaling pathway

eIF6 promotes the malignant progression of human hepatocellular carcinoma via the mTOR signaling pathway

Abstract Background Eukaryotic translation initiation factor 6 (eIF6) has a crucial function in the maturation of 60S ribosomal subunits, and it controls the initiation of protein translation. Although emerging studies indicate that eIF6 is aberrantly expressed in various types of cancers, the funct...

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Bibliographic Details
Main Authors: Liping Sun, Shuguang Liu, Xiaopai Wang, Xuefeng Zheng, Ya Chen, Hong Shen
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Journal of Translational Medicine
Subjects:
EIF6
MTOR
Hepatocellular carcinoma
Cell proliferation
Prognosis
Online Access:https://doi.org/10.1186/s12967-021-02877-4

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