Low dietary fiber intake impairs small intestinal Th17 and intraepithelial T cell development over generations
Summary: Dietary fiber strongly impacts the microbiota. Here, we show that a low-fiber diet changes the small intestinal (SI) microbiota and impairs SI Th17, TCRαβ+CD8αβ+ and TCRαβ+CD8αα+ intraepithelial T cell development. We restore T cell development with dietary fiber supplementation, but this d...
Main Authors: | Charlotte J. Royer, Naomi Rodriguez-Marino, Madelyn D. Yaceczko, Dormarie E. Rivera-Rodriguez, Thomas R. Ziegler, Luisa Cervantes-Barragan |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-10-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221112472301152X |
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