Autonomic Imbalance in Lymphoma Survivors
Among the types of blood cancers, non-Hodgkin lymphoma is the most common. The usual treatments for this type of cancer can cause heart failure. A descriptive observational study was conducted that included 16 non-Hodgkin lymphoma survivors and 16 healthy controls matched by age and sex. Vagal tone...
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MDPI AG
2021-09-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/10/19/4391 |
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| author | Keyla Vargas-Román Jonathan Cortés-Martín Juan Carlos Sánchez-García Raquel Rodríguez-Blanque Emilia Inmaculada De La Fuente-Solana Lourdes Díaz-Rodríguez |
| author_facet | Keyla Vargas-Román Jonathan Cortés-Martín Juan Carlos Sánchez-García Raquel Rodríguez-Blanque Emilia Inmaculada De La Fuente-Solana Lourdes Díaz-Rodríguez |
| author_sort | Keyla Vargas-Román |
| collection | DOAJ |
| description | Among the types of blood cancers, non-Hodgkin lymphoma is the most common. The usual treatments for this type of cancer can cause heart failure. A descriptive observational study was conducted that included 16 non-Hodgkin lymphoma survivors and 16 healthy controls matched by age and sex. Vagal tone was evaluated in the short term with a three-channel Holter device, and the time and frequency domains were analyzed following a previously accepted methodology to evaluate cardiac autonomic balance. The results of the analysis revealed that the standard deviation of the NN interval (F = 6.25, <i>p</i> = 0.021) and the square root of the mean of the sum of the differences between NN intervals (F = 9.74, <i>p</i> = 0.004) were significantly higher in healthy subjects than in lymphoma survivors. In the heart rate variability (HRV) index, there were no significant differences between the groups (F = 0.03, <i>p</i> = 0.85), nor in the parameters of the frequency domains LF (F = 1.94, <i>p</i> = 0.17), HF (F = 0.35, <i>p</i> = 0.55), and the ratio LF/HF (F = 3.07, <i>p</i> = 0.09). HRV values were lower in non-Hodgkin lymphoma survivors in the first year after treatment, resulting in autonomic imbalance compared to healthy paired subjects. |
| first_indexed | 2024-03-10T06:58:11Z |
| format | Article |
| id | doaj.art-abe43a11740f4ebca80131d49fdda9bb |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T06:58:11Z |
| publishDate | 2021-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-abe43a11740f4ebca80131d49fdda9bb2023-11-22T16:18:46ZengMDPI AGJournal of Clinical Medicine2077-03832021-09-011019439110.3390/jcm10194391Autonomic Imbalance in Lymphoma SurvivorsKeyla Vargas-Román0Jonathan Cortés-Martín1Juan Carlos Sánchez-García2Raquel Rodríguez-Blanque3Emilia Inmaculada De La Fuente-Solana4Lourdes Díaz-Rodríguez5Research Group CTS1068, Andalusia Research Plan, Junta de Andalucía, 18014 Granada, SpainResearch Group CTS1068, Andalusia Research Plan, Junta de Andalucía, 18014 Granada, SpainResearch Group CTS1068, Andalusia Research Plan, Junta de Andalucía, 18014 Granada, SpainResearch Group CTS1068, Andalusia Research Plan, Junta de Andalucía, 18014 Granada, SpainMethodology of Behavioral Sciences Department, School of Psychology, University of Granada, 18071 Granada, SpainResearch Group CTS1068, Andalusia Research Plan, Junta de Andalucía, 18014 Granada, SpainAmong the types of blood cancers, non-Hodgkin lymphoma is the most common. The usual treatments for this type of cancer can cause heart failure. A descriptive observational study was conducted that included 16 non-Hodgkin lymphoma survivors and 16 healthy controls matched by age and sex. Vagal tone was evaluated in the short term with a three-channel Holter device, and the time and frequency domains were analyzed following a previously accepted methodology to evaluate cardiac autonomic balance. The results of the analysis revealed that the standard deviation of the NN interval (F = 6.25, <i>p</i> = 0.021) and the square root of the mean of the sum of the differences between NN intervals (F = 9.74, <i>p</i> = 0.004) were significantly higher in healthy subjects than in lymphoma survivors. In the heart rate variability (HRV) index, there were no significant differences between the groups (F = 0.03, <i>p</i> = 0.85), nor in the parameters of the frequency domains LF (F = 1.94, <i>p</i> = 0.17), HF (F = 0.35, <i>p</i> = 0.55), and the ratio LF/HF (F = 3.07, <i>p</i> = 0.09). HRV values were lower in non-Hodgkin lymphoma survivors in the first year after treatment, resulting in autonomic imbalance compared to healthy paired subjects.https://www.mdpi.com/2077-0383/10/19/4391lymphoma cancerHRVautonomic nervous systemnon-Hodgkin lymphoma |
| spellingShingle | Keyla Vargas-Román Jonathan Cortés-Martín Juan Carlos Sánchez-García Raquel Rodríguez-Blanque Emilia Inmaculada De La Fuente-Solana Lourdes Díaz-Rodríguez Autonomic Imbalance in Lymphoma Survivors Journal of Clinical Medicine lymphoma cancer HRV autonomic nervous system non-Hodgkin lymphoma |
| title | Autonomic Imbalance in Lymphoma Survivors |
| title_full | Autonomic Imbalance in Lymphoma Survivors |
| title_fullStr | Autonomic Imbalance in Lymphoma Survivors |
| title_full_unstemmed | Autonomic Imbalance in Lymphoma Survivors |
| title_short | Autonomic Imbalance in Lymphoma Survivors |
| title_sort | autonomic imbalance in lymphoma survivors |
| topic | lymphoma cancer HRV autonomic nervous system non-Hodgkin lymphoma |
| url | https://www.mdpi.com/2077-0383/10/19/4391 |
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