Obstructive sleep apneas naturally occur in mice during REM sleep and are highly prevalent in a mouse model of Down syndrome

Obstructive sleep apneas naturally occur in mice during REM sleep and are highly prevalent in a mouse model of Down syndrome

Study objectives: The use of mouse models in sleep apnea study is limited by the belief that central (CSA) but not obstructive sleep apneas (OSA) occur in rodents. We aimed to develop a protocol to investigate the presence of OSAs in wild-type mice and, then, to apply it to a validated model of Down...

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Bibliographic Details
Main Authors: Maria Lavinia Bartolucci, Chiara Berteotti, Sara Alvente, Stefano Bastianini, Sandra Guidi, Viviana Lo Martire, Gabriele Matteoli, Alessandro Silvani, Fiorenza Stagni, Marcello Bosi, Giulio Alessandri-Bonetti, Renata Bartesaghi, Giovanna Zoccoli
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Neurobiology of Disease
Subjects:
Apneas
Mice
Down syndrome
Breathing
Respiratory disorder
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121002576

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