Association between ischemic heart disease and dietary intake of lycopene: a case–control study
AimThe effect of dietary lycopene on ischemic heart disease (IHD) is not clear. Hence, this study aimed to determine the association between dietary lycopene and IHD.MethodsThis case–control study was conducted on 443 patients with physician confirmed diagnosis of IHD as the case group and 443 healt...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-01-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2023.1281539/full |
| _version_ | 1797362485284569088 |
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| author | Arezoo Amjadi Farkhondeh Alami Mohammad Keshavarz Mohammadian Seyed Reza Mirshafaei Fatemeh Azaryan Anahita Houshiar-Rad Mina Esmaeili Soheila Shekari Morteza Abdollahi Sara Khoshdooz Marjan Ajami Saeid Doaei Maryam Gholamalizadeh |
| author_facet | Arezoo Amjadi Farkhondeh Alami Mohammad Keshavarz Mohammadian Seyed Reza Mirshafaei Fatemeh Azaryan Anahita Houshiar-Rad Mina Esmaeili Soheila Shekari Morteza Abdollahi Sara Khoshdooz Marjan Ajami Saeid Doaei Maryam Gholamalizadeh |
| author_sort | Arezoo Amjadi |
| collection | DOAJ |
| description | AimThe effect of dietary lycopene on ischemic heart disease (IHD) is not clear. Hence, this study aimed to determine the association between dietary lycopene and IHD.MethodsThis case–control study was conducted on 443 patients with physician confirmed diagnosis of IHD as the case group and 443 healthy individuals as the control group. Data on demographic, medical history, anthropometric, and physical activity of the participants were collected. Food intake was evaluated using a 237-item semi-quantitative food frequency questionnaire (FFQ). The dietary intake of lycopene was assessed using Nutritionist IV software.ResultsA negative association was found between IHD and lycopene (OR: 0.98, CI 95%: 0.963–0.996, p = 0.02). The results remained significant after adjustment for age and sex, additional adjustment for dietary intake of calorie and fat, further adjustments for BMI, and additional adjustment for smoking, drinking alcohol, and physical activity. The risk of IHD in people with the highest quartile of dietary intake of lycopene was significantly lower than those with the lowest quartile (OR = 0.67, CI 95%: 0.46–0.97, p = 0.036).ConclusionThere was a significant inverse relationship between intake of lycopene and IHD. Further prospective studies in different populations are required to elucidate the roles of lycopene against IHD. |
| first_indexed | 2024-03-08T16:08:37Z |
| format | Article |
| id | doaj.art-abe8028ae8df44d596f8409b3db99d9e |
| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-03-08T16:08:37Z |
| publishDate | 2024-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-abe8028ae8df44d596f8409b3db99d9e2024-01-08T04:36:42ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2024-01-011010.3389/fnut.2023.12815391281539Association between ischemic heart disease and dietary intake of lycopene: a case–control studyArezoo Amjadi0Farkhondeh Alami1Mohammad Keshavarz Mohammadian2Seyed Reza Mirshafaei3Fatemeh Azaryan4Anahita Houshiar-Rad5Mina Esmaeili6Soheila Shekari7Morteza Abdollahi8Sara Khoshdooz9Marjan Ajami10Saeid Doaei11Maryam Gholamalizadeh12Department of Nutrition, School of Nutritional Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, IranStudent Research Committee, Department of Nutrition, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, IranDepartment of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, IranDepartment of Applied Mathematics, Faculty of Mathematical Sciences, Roudsar and Amlash Branch, Islamic Azad University, Roudsar, IranDepartment of Physiology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, IranDepartment of Nutrition Research, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Nutrition Research, National Nutrition and Food Technology Research Institute, School of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, IranDepartment of Nutrition Research, National Nutrition and Food Technology Research Institute; and Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, IranFaculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran0Department of Food and Nutrition Policy and Planning, National Nutrition and Food Technology Research Institute, School of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran1Department of Community Nutrition, School of Nutrition and Food Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran2Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IranAimThe effect of dietary lycopene on ischemic heart disease (IHD) is not clear. Hence, this study aimed to determine the association between dietary lycopene and IHD.MethodsThis case–control study was conducted on 443 patients with physician confirmed diagnosis of IHD as the case group and 443 healthy individuals as the control group. Data on demographic, medical history, anthropometric, and physical activity of the participants were collected. Food intake was evaluated using a 237-item semi-quantitative food frequency questionnaire (FFQ). The dietary intake of lycopene was assessed using Nutritionist IV software.ResultsA negative association was found between IHD and lycopene (OR: 0.98, CI 95%: 0.963–0.996, p = 0.02). The results remained significant after adjustment for age and sex, additional adjustment for dietary intake of calorie and fat, further adjustments for BMI, and additional adjustment for smoking, drinking alcohol, and physical activity. The risk of IHD in people with the highest quartile of dietary intake of lycopene was significantly lower than those with the lowest quartile (OR = 0.67, CI 95%: 0.46–0.97, p = 0.036).ConclusionThere was a significant inverse relationship between intake of lycopene and IHD. Further prospective studies in different populations are required to elucidate the roles of lycopene against IHD.https://www.frontiersin.org/articles/10.3389/fnut.2023.1281539/fullischemic heart diseaselycopenedietary intakecoronary heart diseaseIHD |
| spellingShingle | Arezoo Amjadi Farkhondeh Alami Mohammad Keshavarz Mohammadian Seyed Reza Mirshafaei Fatemeh Azaryan Anahita Houshiar-Rad Mina Esmaeili Soheila Shekari Morteza Abdollahi Sara Khoshdooz Marjan Ajami Saeid Doaei Maryam Gholamalizadeh Association between ischemic heart disease and dietary intake of lycopene: a case–control study Frontiers in Nutrition ischemic heart disease lycopene dietary intake coronary heart disease IHD |
| title | Association between ischemic heart disease and dietary intake of lycopene: a case–control study |
| title_full | Association between ischemic heart disease and dietary intake of lycopene: a case–control study |
| title_fullStr | Association between ischemic heart disease and dietary intake of lycopene: a case–control study |
| title_full_unstemmed | Association between ischemic heart disease and dietary intake of lycopene: a case–control study |
| title_short | Association between ischemic heart disease and dietary intake of lycopene: a case–control study |
| title_sort | association between ischemic heart disease and dietary intake of lycopene a case control study |
| topic | ischemic heart disease lycopene dietary intake coronary heart disease IHD |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2023.1281539/full |
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