Astragalus Polysaccharides/Chitosan Microspheres for Nasal Delivery: Preparation, Optimization, Characterization, and Pharmacodynamics

Astragalus Polysaccharides/Chitosan Microspheres for Nasal Delivery: Preparation, Optimization, Characterization, and Pharmacodynamics

Chitosan (CTS) constitutes a promising area in treatment of nose-related diseases as a nasal drug delivery carrier. Astragalus polysaccharide (APS) significantly attenuates eosinophils and neutrophil-dominant airway inflammation, and it has a potential pharmaceutical application in the treatment of...

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Bibliographic Details
Main Authors: Saisai Wang, Yuqing Sun, Jingjing Zhang, Xiaoming Cui, Zhilu Xu, Dejun Ding, Limin Zhao, Wentong Li, Weifen Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Pharmacology
Subjects:
Chitosan
Astragalus polysaccharide
spray drying
microspheres
nasal drug delivery
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00230/full

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