| Summary: | Introduction. Acute lower limb ischemia results from thrombosis or
embolization of diseased native artery or previously implanted bypass graft.
When this occurs, several options are available to restore blood flow:
catheter-directed thrombolysis, mechanical thrombectomy or open surgery.
Fundamental reasons to apply percutaneous interventions are avoiding open
procedures in high risk patients, and avoiding difficult dissection through
scar tissue. Case Outline. A 67-year-old male was admitted at our Institution
for critical limb ischemia. After performed angiography the diagnosis of
occluded femoropopliteal graft was established. Occlusion was resolved by
catheter-directed thrombolysis with plasmin. Culprit lesions were treated by
angioplasty. Conclusion. Our patient underwent a successful thrombolysis of
occluded femoropopliteal graft with locally-delivered human plasmin.
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