Association patterns of Atrial Fibrillation with symptoms of metabolic syndrome
Background: Atrial fibrillation (AF) is the common cardiac arrhythmia in which heart beats irregularly usually greater than 100 beats per minutes. AF is well-documented public health problem causing substantial mortality and morbidity. Metabolic syndrome (MS) is a collection of metabolic risk factor...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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The Running Line
2017-05-01
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| Series: | Advancements in Life Sciences |
| Subjects: | |
| Online Access: | http://www.als-journal.com/434-17/ |
| _version_ | 1797710316547604480 |
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| author | Saima Sharif Tasnim Farasat Saira Rafaqat Shagufta Naz Farkhanda Manzoor Muhammad Saqib |
| author_facet | Saima Sharif Tasnim Farasat Saira Rafaqat Shagufta Naz Farkhanda Manzoor Muhammad Saqib |
| author_sort | Saima Sharif |
| collection | DOAJ |
| description | Background: Atrial fibrillation (AF) is the common cardiac arrhythmia in which heart beats irregularly usually greater than 100 beats per minutes. AF is well-documented public health problem causing substantial mortality and morbidity. Metabolic syndrome (MS) is a collection of metabolic risk factors like diabetes, hypertension, dyslipidemia, obesity and impaired glucose level that exists in one person. The aim of the present study is to find the relation between AF and MS.
Methods: 100 patients of AF were sampled from Punjab Institute of Cardiology, Lahore from December, 2014 to June 2015. These patients were divided into two AF groups, 50 without MS and 50 with MS. 25 healthy subjects were also included for the comparison. Lipid profile was assessed by chemistry analyzer and serum insulin was measured by ELISA.
Results: In our population, there was significantly high levels of insulin resistance (IR) and obesity in AF groups (without MS and with MS) as compared with healthy subjects (P<0.05). Highly significant differences was observed in relation with other parameters e.g. hypertension, hypertriglyceridemia, HDL-C among the studied groups (P<0.05). Significant positive correlation was observed between insulin and lipid profile (TC, TG, LDL) while inverse with HDL.
Conclusion: The indictors of metabolic syndrome were significantly correlated with AF in the studied subjects, while IR was found significantly higher in MS group. |
| first_indexed | 2024-03-12T06:49:30Z |
| format | Article |
| id | doaj.art-abe9cd50aaf5441086e66820ccb99ea6 |
| institution | Directory Open Access Journal |
| issn | 2310-5380 2310-5380 |
| language | English |
| last_indexed | 2024-03-12T06:49:30Z |
| publishDate | 2017-05-01 |
| publisher | The Running Line |
| record_format | Article |
| series | Advancements in Life Sciences |
| spelling | doaj.art-abe9cd50aaf5441086e66820ccb99ea62023-09-03T00:22:32ZengThe Running LineAdvancements in Life Sciences2310-53802310-53802017-05-01439296Association patterns of Atrial Fibrillation with symptoms of metabolic syndromeSaima Sharif0Tasnim Farasat1Saira Rafaqat2Shagufta Naz3Farkhanda Manzoor4Muhammad Saqib5Department of Zoology, Lahore College for Women University, Lahore – PakistanDepartment of Zoology, Lahore College for Women University, Lahore – PakistanDepartment of Zoology, Lahore College for Women University, Lahore – PakistanDepartment of Zoology, Lahore College for Women University, Lahore – PakistanDepartment of Zoology, Lahore College for Women University, Lahore – Pakistan Jinnah Hospital Lahore – PakistanBackground: Atrial fibrillation (AF) is the common cardiac arrhythmia in which heart beats irregularly usually greater than 100 beats per minutes. AF is well-documented public health problem causing substantial mortality and morbidity. Metabolic syndrome (MS) is a collection of metabolic risk factors like diabetes, hypertension, dyslipidemia, obesity and impaired glucose level that exists in one person. The aim of the present study is to find the relation between AF and MS. Methods: 100 patients of AF were sampled from Punjab Institute of Cardiology, Lahore from December, 2014 to June 2015. These patients were divided into two AF groups, 50 without MS and 50 with MS. 25 healthy subjects were also included for the comparison. Lipid profile was assessed by chemistry analyzer and serum insulin was measured by ELISA. Results: In our population, there was significantly high levels of insulin resistance (IR) and obesity in AF groups (without MS and with MS) as compared with healthy subjects (P<0.05). Highly significant differences was observed in relation with other parameters e.g. hypertension, hypertriglyceridemia, HDL-C among the studied groups (P<0.05). Significant positive correlation was observed between insulin and lipid profile (TC, TG, LDL) while inverse with HDL. Conclusion: The indictors of metabolic syndrome were significantly correlated with AF in the studied subjects, while IR was found significantly higher in MS group.http://www.als-journal.com/434-17/Atrial Fibrillationmetabolic syndrome |
| spellingShingle | Saima Sharif Tasnim Farasat Saira Rafaqat Shagufta Naz Farkhanda Manzoor Muhammad Saqib Association patterns of Atrial Fibrillation with symptoms of metabolic syndrome Advancements in Life Sciences Atrial Fibrillation metabolic syndrome |
| title | Association patterns of Atrial Fibrillation with symptoms of metabolic syndrome |
| title_full | Association patterns of Atrial Fibrillation with symptoms of metabolic syndrome |
| title_fullStr | Association patterns of Atrial Fibrillation with symptoms of metabolic syndrome |
| title_full_unstemmed | Association patterns of Atrial Fibrillation with symptoms of metabolic syndrome |
| title_short | Association patterns of Atrial Fibrillation with symptoms of metabolic syndrome |
| title_sort | association patterns of atrial fibrillation with symptoms of metabolic syndrome |
| topic | Atrial Fibrillation metabolic syndrome |
| url | http://www.als-journal.com/434-17/ |
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