Inhibitory Effects of Copper, Brass, and Stainless Steel Surfaces on Multidrug-Resistant Microorganisms
Background: The aim of this study was to analyze the inhibitory effects of copper, brass (78% copper, 22% tin), and stainless steel surfaces on multidrug-resistant Acinetobacter baumannii (MRAB), extended-spectrum beta-lactamase (ESBL) Escherichia coli, and carbapenem-resistant Klebsiella pneumoniae...
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| Format: | Article |
| Language: | English |
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Korean Society of Clinical Microbiology
2022-06-01
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| Series: | Annals of Clinical Microbiology |
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| Online Access: | https://www.acm.or.kr/acm_22-001/ |
| _version_ | 1818490306740355072 |
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| author | Jung-Beom Kim Jae-Kwang Kim Jaewoong Lee Hiun Suk Chae Hae Kyung Lee Yeon- Joon Park |
| author_facet | Jung-Beom Kim Jae-Kwang Kim Jaewoong Lee Hiun Suk Chae Hae Kyung Lee Yeon- Joon Park |
| author_sort | Jung-Beom Kim |
| collection | DOAJ |
| description | Background: The aim of this study was to analyze the inhibitory effects of copper, brass (78% copper, 22% tin), and stainless steel surfaces on multidrug-resistant Acinetobacter baumannii (MRAB), extended-spectrum beta-lactamase (ESBL) Escherichia coli, and carbapenem-resistant Klebsiella pneumoniae (CRKP).
Methods: MRAB, ESBL E. coli, and CRKP were isolated at Uijeongbu St.Mary’s Hospital in 2020. A. baumannii ATCC BAA-747, E. coli ATCC 25922, and K. pneumoniae ATCC 700603 were used as reference strains. The initial bacterial cell count of each inoculum was adjusted to 8 log CFU/mL using phosphate buffered saline, Copper, brass, and stainless steel plates were inoculated with 9 mL of MRAB, ESBL E. coli, and CRKP inoculum solutions. The bacterial cell count was measured from the beginning to the 20th day in an incubator maintained at 35°C.
Results: MRAB, ESBL E. coli, and CRKP isolates were not detected on the copper and brass plates after 4, 5.5, and 6.5 hours, respectively. MRAB, ESBL E. coli, and CRKP isolates were not detected on the stainless steel plate after 15, 20, and 20 days, respectively. The bactericidal effects of copper and brass were much stronger than those of stainless steel.
Conclusion: The use of copper and copper alloys should be considered to prevent cross-infection in hospitals. |
| first_indexed | 2024-12-10T17:15:07Z |
| format | Article |
| id | doaj.art-abee92fbcebd47a59a9579ad2775e18d |
| institution | Directory Open Access Journal |
| issn | 2288-0585 2288-6850 |
| language | English |
| last_indexed | 2024-12-10T17:15:07Z |
| publishDate | 2022-06-01 |
| publisher | Korean Society of Clinical Microbiology |
| record_format | Article |
| series | Annals of Clinical Microbiology |
| spelling | doaj.art-abee92fbcebd47a59a9579ad2775e18d2022-12-22T01:40:10ZengKorean Society of Clinical MicrobiologyAnnals of Clinical Microbiology2288-05852288-68502022-06-01252354410.5145/ACM.2022.25.2.1Inhibitory Effects of Copper, Brass, and Stainless Steel Surfaces on Multidrug-Resistant MicroorganismsJung-Beom Kim0Jae-Kwang Kim1Jaewoong Lee2Hiun Suk Chae3Hae Kyung Lee4Yeon- Joon Park5Department of Food Science and Technology, Sunchon National University, SuncheonDepartment of Laboratory Medicine, Uijeongbu St.Mary’s Hospital, The Catholic University of Korea, UijeongbuIncheon St.Mary’s Hospital, IncheonDepartment of Internal Medicine, Uijeongbu St. Mary’s Hospital, UijeongbuDepartment of Laboratory Medicine, Seoul St. Mary’s Hospital, Seoul, KoreaDepartment of Laboratory Medicine, Seoul St. Mary’s Hospital, Seoul, KoreaBackground: The aim of this study was to analyze the inhibitory effects of copper, brass (78% copper, 22% tin), and stainless steel surfaces on multidrug-resistant Acinetobacter baumannii (MRAB), extended-spectrum beta-lactamase (ESBL) Escherichia coli, and carbapenem-resistant Klebsiella pneumoniae (CRKP). Methods: MRAB, ESBL E. coli, and CRKP were isolated at Uijeongbu St.Mary’s Hospital in 2020. A. baumannii ATCC BAA-747, E. coli ATCC 25922, and K. pneumoniae ATCC 700603 were used as reference strains. The initial bacterial cell count of each inoculum was adjusted to 8 log CFU/mL using phosphate buffered saline, Copper, brass, and stainless steel plates were inoculated with 9 mL of MRAB, ESBL E. coli, and CRKP inoculum solutions. The bacterial cell count was measured from the beginning to the 20th day in an incubator maintained at 35°C. Results: MRAB, ESBL E. coli, and CRKP isolates were not detected on the copper and brass plates after 4, 5.5, and 6.5 hours, respectively. MRAB, ESBL E. coli, and CRKP isolates were not detected on the stainless steel plate after 15, 20, and 20 days, respectively. The bactericidal effects of copper and brass were much stronger than those of stainless steel. Conclusion: The use of copper and copper alloys should be considered to prevent cross-infection in hospitals.https://www.acm.or.kr/acm_22-001/bactericidal effectbrasscoppermultidrug-resistant bacteria |
| spellingShingle | Jung-Beom Kim Jae-Kwang Kim Jaewoong Lee Hiun Suk Chae Hae Kyung Lee Yeon- Joon Park Inhibitory Effects of Copper, Brass, and Stainless Steel Surfaces on Multidrug-Resistant Microorganisms Annals of Clinical Microbiology bactericidal effect brass copper multidrug-resistant bacteria |
| title | Inhibitory Effects of Copper, Brass, and Stainless Steel Surfaces on Multidrug-Resistant Microorganisms |
| title_full | Inhibitory Effects of Copper, Brass, and Stainless Steel Surfaces on Multidrug-Resistant Microorganisms |
| title_fullStr | Inhibitory Effects of Copper, Brass, and Stainless Steel Surfaces on Multidrug-Resistant Microorganisms |
| title_full_unstemmed | Inhibitory Effects of Copper, Brass, and Stainless Steel Surfaces on Multidrug-Resistant Microorganisms |
| title_short | Inhibitory Effects of Copper, Brass, and Stainless Steel Surfaces on Multidrug-Resistant Microorganisms |
| title_sort | inhibitory effects of copper brass and stainless steel surfaces on multidrug resistant microorganisms |
| topic | bactericidal effect brass copper multidrug-resistant bacteria |
| url | https://www.acm.or.kr/acm_22-001/ |
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