Exosomal HMGB1 Promoted Cancer Malignancy

Exosomal HMGB1 Promoted Cancer Malignancy

Reciprocal crosstalk between platelets and malignancies underscores the potential of antiplatelet therapy in cancer treatment. In this study, we found that human chronic myeloid leukemia K562 cell-differentiated megakaryocytes and murine platelets produced bioactive substances and these are released...

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Bibliographic Details
Main Authors: Jiaan-Der Wang, Ya-Yu Wang, Shih-Yi Lin, Cheng-Yi Chang, Jian-Ri Li, Shi-Wei Huang, Wen-Ying Chen, Su-Lan Liao, Chun-Jung Chen
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
antiplatelet
exosome
HMGB1
malignancy
Online Access:https://www.mdpi.com/2072-6694/13/4/877

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