Aversion to Desflurane and Isoflurane in Sprague-Dawley Rats (<i>Rattus norvegicus</i>)

Aversion to Desflurane and Isoflurane in Sprague-Dawley Rats (<i>Rattus norvegicus</i>)

Carbon dioxide and isoflurane are widely used for killing rats, yet may not truly achieve “euthanasia”, because they elicit aversion. The inhalant anesthetic desflurane is faster acting than isoflurane, representing a potential refinement. Using an aversion-avoidance paradigm, 24 rats were exposed t...

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Bibliographic Details
Main Authors:	Katrina Frost, Maaria Shah, Vivian S.Y. Leung, Daniel S.J. Pang
Format:	Article
Language:	English
Published:	MDPI AG 2020-05-01
Series:	Animals
Subjects:	euthanasia rats animal welfare refinement aversion isoflurane
Online Access:	https://www.mdpi.com/2076-2615/10/6/950

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