The influence of the factor of pathogenicity of Helicobacter pylori dupa on the nature of the morphological picture of gastric mucosa in diseases of the upper gastrointestinal tract in children

Helicobacter pylori (H. pylori) is a key factor in the etiology of various gastrointestinal diseases. The interaction analysis of a pathogenicity factor of H. pylori dupA and morphological changes in the gastric mucosa (GM) in children with chronic inflammatory diseases of the upper gastrointestinal...

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Main Authors: E. V. Dudnikova, E. V. Gilis, V. G. Zaz'yan, A. V. Zaz'yan, M. S. Chernova
Format: Article
Language:Russian
Published: Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” 2016-06-01
Series:Кубанский научный медицинский вестник
Subjects:
Online Access:https://ksma.elpub.ru/jour/article/view/521
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author E. V. Dudnikova
E. V. Gilis
V. G. Zaz'yan
A. V. Zaz'yan
M. S. Chernova
author_facet E. V. Dudnikova
E. V. Gilis
V. G. Zaz'yan
A. V. Zaz'yan
M. S. Chernova
author_sort E. V. Dudnikova
collection DOAJ
description Helicobacter pylori (H. pylori) is a key factor in the etiology of various gastrointestinal diseases. The interaction analysis of a pathogenicity factor of H. pylori dupA and morphological changes in the gastric mucosa (GM) in children with chronic inflammatory diseases of the upper gastrointestinal tract (GIT). The results show the influence of this factor on the pathogenicity on the severity of clinical disease. I n this study the dependence of the formation of gastritis high degree of activity, and the incidence of sclerotic and dystrophic changes in the coolant depending on the carrier dupA gene have been identified. However, the presence of dupA gene was associated with a low chance of developing atrophy.
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spelling doaj.art-abf63b79539d48a487e82fca86914a682025-03-02T10:05:27ZrusMinistry of Healthcare of the Russian Federation. “Kuban State Medical University”Кубанский научный медицинский вестник1608-62282541-95442016-06-0135962521The influence of the factor of pathogenicity of Helicobacter pylori dupa on the nature of the morphological picture of gastric mucosa in diseases of the upper gastrointestinal tract in childrenE. V. Dudnikova0E. V. Gilis1V. G. Zaz'yan2A. V. Zaz'yan3M. S. Chernova4State educational Institute of high professional training «The Rostov state medical university»State educational Institute of high professional training «The Rostov state medical university»State educational Institute of high professional training «The Rostov state medical university»State educational Institute of high professional training «The Rostov state medical university»State educational Institute of high professional training «The Rostov state medical university»Helicobacter pylori (H. pylori) is a key factor in the etiology of various gastrointestinal diseases. The interaction analysis of a pathogenicity factor of H. pylori dupA and morphological changes in the gastric mucosa (GM) in children with chronic inflammatory diseases of the upper gastrointestinal tract (GIT). The results show the influence of this factor on the pathogenicity on the severity of clinical disease. I n this study the dependence of the formation of gastritis high degree of activity, and the incidence of sclerotic and dystrophic changes in the coolant depending on the carrier dupA gene have been identified. However, the presence of dupA gene was associated with a low chance of developing atrophy.https://ksma.elpub.ru/jour/article/view/521h. pyloriфакторы патогенностиdupaхронический гастритдетиh. pyloripathogenicity factorsdupachronic gastritischildren
spellingShingle E. V. Dudnikova
E. V. Gilis
V. G. Zaz'yan
A. V. Zaz'yan
M. S. Chernova
The influence of the factor of pathogenicity of Helicobacter pylori dupa on the nature of the morphological picture of gastric mucosa in diseases of the upper gastrointestinal tract in children
Кубанский научный медицинский вестник
h. pylori
факторы патогенности
dupa
хронический гастрит
дети
h. pylori
pathogenicity factors
dupa
chronic gastritis
children
title The influence of the factor of pathogenicity of Helicobacter pylori dupa on the nature of the morphological picture of gastric mucosa in diseases of the upper gastrointestinal tract in children
title_full The influence of the factor of pathogenicity of Helicobacter pylori dupa on the nature of the morphological picture of gastric mucosa in diseases of the upper gastrointestinal tract in children
title_fullStr The influence of the factor of pathogenicity of Helicobacter pylori dupa on the nature of the morphological picture of gastric mucosa in diseases of the upper gastrointestinal tract in children
title_full_unstemmed The influence of the factor of pathogenicity of Helicobacter pylori dupa on the nature of the morphological picture of gastric mucosa in diseases of the upper gastrointestinal tract in children
title_short The influence of the factor of pathogenicity of Helicobacter pylori dupa on the nature of the morphological picture of gastric mucosa in diseases of the upper gastrointestinal tract in children
title_sort influence of the factor of pathogenicity of helicobacter pylori dupa on the nature of the morphological picture of gastric mucosa in diseases of the upper gastrointestinal tract in children
topic h. pylori
факторы патогенности
dupa
хронический гастрит
дети
h. pylori
pathogenicity factors
dupa
chronic gastritis
children
url https://ksma.elpub.ru/jour/article/view/521
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